OBJECTIVES: To compare the association between self-reported moderate to severe pain and frailty. DESIGN: Cross-sectional analysis of the Canadian Study of Health and Aging Wave 2. SETTING: Community. PARTICIPANTS: Representative sample of persons aged 65 and older in Canada. MEASUREMENTS: Pain (exposure) was categorized as no or very mild pain versus moderate or greater pain. Frailty (outcome) was operationalized as the accumulation of 33 possible self-reported health attitudes, illnesses, and functional abilities, subsequently divided into tertiles (not frail, prefrail, and frail). Multivariable logistic regression assessed for the association between pain and frailty. RESULTS: Of participants who reported moderate or greater pain (35.5%, 1,765/4,968), 16.2% were not frail, 34.1% were prefrail, and 49.8% were frail. For persons with moderate or greater pain, the odds of being prefrail rather than not frail were higher by a factor of 2.52 (95% confidence interval (CI) = 2.13-2.99; P < .001). For persons with moderate or greater pain, the odds of being frail rather than not frail were higher by a factor of 5.52 (95% CI = 4.49-6.64 P < .001). CONCLUSION: Moderate or higher pain was independently associated with frailty. Although causality cannot be ascertained in a cross-sectional analysis, interventions to improve pain management may help prevent or ameliorate frailty.
OBJECTIVES: To compare the association between self-reported moderate to severe pain and frailty. DESIGN: Cross-sectional analysis of the Canadian Study of Health and Aging Wave 2. SETTING: Community. PARTICIPANTS: Representative sample of persons aged 65 and older in Canada. MEASUREMENTS: Pain (exposure) was categorized as no or very mild pain versus moderate or greater pain. Frailty (outcome) was operationalized as the accumulation of 33 possible self-reported health attitudes, illnesses, and functional abilities, subsequently divided into tertiles (not frail, prefrail, and frail). Multivariable logistic regression assessed for the association between pain and frailty. RESULTS: Of participants who reported moderate or greater pain (35.5%, 1,765/4,968), 16.2% were not frail, 34.1% were prefrail, and 49.8% were frail. For persons with moderate or greater pain, the odds of being prefrail rather than not frail were higher by a factor of 2.52 (95% confidence interval (CI) = 2.13-2.99; P < .001). For persons with moderate or greater pain, the odds of being frail rather than not frail were higher by a factor of 5.52 (95% CI = 4.49-6.64 P < .001). CONCLUSION: Moderate or higher pain was independently associated with frailty. Although causality cannot be ascertained in a cross-sectional analysis, interventions to improve pain management may help prevent or ameliorate frailty.
Authors: Arnold Mitnitski; Xiaowei Song; Ingmar Skoog; G A Broe; Jafna L Cox; Eva Grunfeld; Kenneth Rockwood Journal: J Am Geriatr Soc Date: 2005-12 Impact factor: 5.562
Authors: Joseph Shega; Linda Emanuel; Lisa Vargish; Stacie K Levine; Heide Bursch; Keela Herr; Jordan F Karp; Debra K Weiner Journal: J Pain Date: 2007-05 Impact factor: 5.820
Authors: Maria Luisa Bianchi; Maria Rosa Orsini; Silvia Saraifoger; Sergio Ortolani; Giovanni Radaelli; Simonetta Betti Journal: Health Qual Life Outcomes Date: 2005-12-01 Impact factor: 3.186
Authors: Matthew C Lohman; Karen L Whiteman; Rebecca L Greenberg; Martha L Bruce Journal: J Gerontol A Biol Sci Med Sci Date: 2016-10-21 Impact factor: 6.053
Authors: Lauren R Pollack; Nathan E Goldstein; Wendy C Gonzalez; Craig D Blinderman; Mathew S Maurer; David J Lederer; Matthew R Baldwin Journal: J Am Geriatr Soc Date: 2017-03-06 Impact factor: 5.562
Authors: Joseph W Shega; Melissa Andrew; Ashwin Kotwal; Denys T Lau; Keela Herr; Mary Ersek; Debra K Weiner; Marshall H Chin; William Dale Journal: J Am Geriatr Soc Date: 2013-12-09 Impact factor: 5.562
Authors: Anatoliy I Yashin; Konstantin G Arbeev; Liubov S Arbeeva; Deqing Wu; Igor Akushevich; Mikhail Kovtun; Arseniy Yashkin; Alexander Kulminski; Irina Culminskaya; Eric Stallard; Miaozhu Li; Svetlana V Ukraintseva Journal: Biogerontology Date: 2015-08-18 Impact factor: 4.277
Authors: Kyle M Baumbauer; Erin E Young; Angela R Starkweather; Jessica W Guite; Beth S Russell; Renee C B Manworren Journal: Med Clin North Am Date: 2016-01 Impact factor: 5.456
Authors: Marjaana P H Koponen; J Simon Bell; Niina M Karttunen; Irma A Nykänen; Franciska A M Desplenter; Sirpa A Hartikainen Journal: Drugs Aging Date: 2013-02 Impact factor: 3.923