PURPOSE: The recent introduction of a specific electronic readout chip, designed for the processing of the same signal pulses from an x-ray sensor in one integrating and one counting channel in each pixel E. Kraft et al., [IEEE Trans. Nucl. Sci. 54, 383-390 (2007)]; E. Kraft, "Counting and integrating microelectronics development for direct conversion X-ray imaging," Ph.D. thesis, 2007; J. Fink, "Characterization of the imaging performance of the simultaneously counting and integrating X-ray detector CIX," Ph.D. thesis, 2010, enables an alternative to conventional dual-energy imaging methods. As shown in a previous paper, the proposed alternative benefits from positively correlated noise in the raw data, inherent to the counting-integrating readout (CIX), which results in a reduction of basis image noise after dual-energy decomposition. In the present paper, the authors compare the new approach to dual-energy imaging to two conventional dual-energy techniques, the dual-kV technique and the dual-crystal technique and to a photon-counting technique based on two energy windows. METHODS: The study is based on x-ray computed tomography (CT) simulations of an anthropomorphic head phantom, where the signal-to-noise ratios and the contrast-to-noise ratios in basis material images and quasi-monochromatic images at 60 keV are compared. Moreover, a simple pictorial illustration of the relevance of input noise correlations in the noise-propagation process during the dual-energy basis material decomposition are presented, as well as measurement data for the correlation obtained as a function of the x-ray flux rate. RESULTS: Under the idealized assumptions of the absence of scatter and detector imperfections like K-escape, crosstalk and detector noise, our comparison shows that among the dual-energy techniques investigated, the CIX concept together with the dual-kV technique performs best, confirming the mitigating effect of correlated measurement data on the dual-energy basis material decomposition. CONCLUSIONS: The novel concept of simultaneous counting of photons and integrating the x-ray energy flux has a large potential for dual-energy applications in both projection and tomographic x-ray imaging. Future work will have to focus on the sensitivity of the CIX dual-energy concept to scattered radiation, detector imperfections and high x-ray fluxes.
PURPOSE: The recent introduction of a specific electronic readout chip, designed for the processing of the same signal pulses from an x-ray sensor in one integrating and one counting channel in each pixel E. Kraft et al., [IEEE Trans. Nucl. Sci. 54, 383-390 (2007)]; E. Kraft, "Counting and integrating microelectronics development for direct conversion X-ray imaging," Ph.D. thesis, 2007; J. Fink, "Characterization of the imaging performance of the simultaneously counting and integrating X-ray detector CIX," Ph.D. thesis, 2010, enables an alternative to conventional dual-energy imaging methods. As shown in a previous paper, the proposed alternative benefits from positively correlated noise in the raw data, inherent to the counting-integrating readout (CIX), which results in a reduction of basis image noise after dual-energy decomposition. In the present paper, the authors compare the new approach to dual-energy imaging to two conventional dual-energy techniques, the dual-kV technique and the dual-crystal technique and to a photon-counting technique based on two energy windows. METHODS: The study is based on x-ray computed tomography (CT) simulations of an anthropomorphic head phantom, where the signal-to-noise ratios and the contrast-to-noise ratios in basis material images and quasi-monochromatic images at 60 keV are compared. Moreover, a simple pictorial illustration of the relevance of input noise correlations in the noise-propagation process during the dual-energy basis material decomposition are presented, as well as measurement data for the correlation obtained as a function of the x-ray flux rate. RESULTS: Under the idealized assumptions of the absence of scatter and detector imperfections like K-escape, crosstalk and detector noise, our comparison shows that among the dual-energy techniques investigated, the CIX concept together with the dual-kV technique performs best, confirming the mitigating effect of correlated measurement data on the dual-energy basis material decomposition. CONCLUSIONS: The novel concept of simultaneous counting of photons and integrating the x-ray energy flux has a large potential for dual-energy applications in both projection and tomographic x-ray imaging. Future work will have to focus on the sensitivity of the CIX dual-energy concept to scattered radiation, detector imperfections and high x-ray fluxes.
Authors: Dipanjan Pan; Carsten O Schirra; Samuel A Wickline; Gregory M Lanza Journal: Contrast Media Mol Imaging Date: 2014 Jan-Feb Impact factor: 3.161