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Literature DB >> 22148829

Directed Arbuzov-type reactions of 2-cyano-1,1-dimethylethyl deoxynucleoside phosphites.

J Nielsen, M H Caruthers.

Abstract

Entities: Chemical

Year: 1988 PMID： 22148829 DOI： 10.1021/ja00226a069

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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7 in total

1. Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.

Authors: Naoki Iwamoto; David C D Butler; Nenad Svrzikapa; Susovan Mohapatra; Ivan Zlatev; Dinah W Y Sah; Stephany M Standley; Genliang Lu; Luciano H Apponi; Maria Frank-Kamenetsky; Jason Jingxin Zhang; Chandra Vargeese; Gregory L Verdine
Journal: Nat Biotechnol Date: 2017-08-21 Impact factor: 54.908

2. Catalytic asymmetric and stereodivergent oligonucleotide synthesis.

Authors: Aaron L Featherston; Yongseok Kwon; Matthew M Pompeo; Oliver D Engl; David K Leahy; Scott J Miller
Journal: Science Date: 2021-02-12 Impact factor: 47.728

Review 3. Synthesis of DNA/RNA and their analogs via phosphoramidite and H-phosphonate chemistries.

Authors: Subhadeep Roy; Marvin Caruthers
Journal: Molecules Date: 2013-11-18 Impact factor: 4.411

4. Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.

Authors: S K Miroshnichenko; O A Patutina; E A Burakova; B P Chelobanov; A A Fokina; V V Vlassov; S Altman; M A Zenkova; D A Stetsenko
Journal: Proc Natl Acad Sci U S A Date: 2019-01-08 Impact factor: 11.205

Directed Arbuzov-type reactions of 2-cyano-1,1-dimethylethyl deoxynucleoside phosphites.

1. Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.

2. Catalytic asymmetric and stereodivergent oligonucleotide synthesis.

Review 3. Synthesis of DNA/RNA and their analogs via phosphoramidite and H-phosphonate chemistries.

4. Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.

Review 5. Opening up the Toolbox: Synthesis and Mechanisms of Phosphoramidates.

6. Conjugation of chemical handles and functional moieties to DNA during solid phase synthesis with sulfonyl azides.

7. Transport Oligonucleotides-A Novel System for Intracellular Delivery of Antisense Therapeutics.