Literature DB >> 22147345

Isochromosome 17q, MYC amplification and large cell/anaplastic phenotype in a case of medullomyoblastoma with extracranial metastases.

Karen D Wright1, Kendra von der Embse, Jamie Coleman, Zoltan Patay, David W Ellison, Amar Gajjar.   

Abstract

Medullomyoblastoma (MMB) is a rare variant of medulloblastoma, a member of the family of central nervous system (CNS) embryonal tumors. The outcome of standard therapy for CNS embryonal tumors is often unpredictable in the setting of MMB. Here, we present the clinical course and treatment of an almost 4-year-old girl with MMB that was characterized by MYC amplification, isochromosome 17q and large cell/anaplastic histopathology.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID： 22147345      PMCID： PMC3392450          DOI： 10.1002/pbc.24002

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN： 1545-5009            Impact factor:   3.167


  18 in total

1.  "Large cell/anaplastic" medulloblastomas: a Pediatric Oncology Group Study.

Authors:  H G Brown; J L Kepner; E J Perlman; H S Friedman; D R Strother; P K Duffner; L E Kun; P T Goldthwaite; P C Burger
Journal:  J Neuropathol Exp Neurol       Date:  2000-10       Impact factor: 3.685

2.  Unusually long survival in a case of medullomyoblastoma.

Authors:  Awadhesh Kumar Jaiswal; Sushila Jaiswal; Ashok Kumar Mahapatra; Mehar Chand Sharma
Journal:  J Clin Neurosci       Date:  2005-11       Impact factor: 1.961

3.  Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study.

Authors:  Charles G Eberhart; James L Kepner; Patricia T Goldthwaite; Larry E Kun; Patricia K Duffner; Henry S Friedman; Douglas R Strother; Peter C Burger
Journal:  Cancer       Date:  2002-01-15       Impact factor: 6.860

4.  MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group.

Authors:  Naji Aldosari; Sandra H Bigner; Peter C Burger; Laurence Becker; James L Kepner; Henry S Friedman; Roger E McLendon
Journal:  Arch Pathol Lab Med       Date:  2002-05       Impact factor: 5.534

5.  Medulloblastoma comprises four distinct molecular variants.

Authors:  Paul A Northcott; Andrey Korshunov; Hendrik Witt; Thomas Hielscher; Charles G Eberhart; Stephen Mack; Eric Bouffet; Steven C Clifford; Cynthia E Hawkins; Pim French; James T Rutka; Stefan Pfister; Michael D Taylor
Journal:  J Clin Oncol       Date:  2010-09-07       Impact factor: 44.544

Review 6.  Classifying the medulloblastoma: insights from morphology and molecular genetics.

Authors:  D Ellison
Journal:  Neuropathol Appl Neurobiol       Date:  2002-08       Impact factor: 8.090

7.  Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients.

Authors:  Jayne M Lamont; Charles S McManamy; Andrew D Pearson; Steven C Clifford; David W Ellison
Journal:  Clin Cancer Res       Date:  2004-08-15       Impact factor: 12.531

Review 8.  Medullomyoblastoma: a radiographic and clinicopathologic analysis of six cases and review of the literature.

Authors:  Kathleen J Helton; Maryam Fouladi; Frederick A Boop; Arie Perry; James Dalton; Larry Kun; Christine Fuller
Journal:  Cancer       Date:  2004-09-15       Impact factor: 6.860

9.  Prognostic significance of chromosome 17p deletions in childhood primitive neuroectodermal tumors (medulloblastomas) of the central nervous system.

Authors:  J A Biegel; A J Janss; C Raffel; L Sutton; L B Rorke; J M Harper; P C Phillips
Journal:  Clin Cancer Res       Date:  1997-03       Impact factor: 12.531

10.  N-myc and c-myc oncogenes amplification in medulloblastomas. Evidence of particularly aggressive behavior of a tumor with c-myc amplification.

Authors:  M Badiali; A Pession; G Basso; L Andreini; L Rigobello; E Galassi; F Giangaspero
Journal:  Tumori       Date:  1991-04-30
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  3 in total

Review 1.  Medulloblastoma.

Authors:  Nathan E Millard; Kevin C De Braganca
Journal:  J Child Neurol       Date:  2015-09-02       Impact factor: 1.987

2.  Isochromosome 17q in Chronic Lymphocytic Leukemia.

Authors:  Eyad Alhourani; Martina Rincic; Joana B Melo; Isabel M Carreira; Anita Glaser; Beate Pohle; Cordula Schlie; Thomas Liehr
Journal:  Leuk Res Treatment       Date:  2015-11-30

3.  Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia.

Authors:  Jingying Xu; Ashley Sloane Margol; Anju Shukla; Xiuhai Ren; Jonathan L Finlay; Mark D Krieger; Floyd H Gilles; Fergus J Couch; Meraj Aziz; Eric T Fung; Shahab Asgharzadeh; Michael T Barrett; Anat Erdreich-Epstein
Journal:  Front Oncol       Date:  2015-08-27       Impact factor: 6.244
  3 in total

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