Literature DB >> 22147043

Cutaneous leiomyosarcoma on the trunk.

Marisa Carpinteiro André1, Joana Veiga Antunes, Miguel Duarte Reis, Paulo Leal Filipe, Luís Miguel Soares de Almeida.   

Abstract

Cutaneous leiomyosarcoma is a relatively uncommon tumor that accounts for 7% of all soft tissue sarcomas. It occurs more frequently in males between 50-70 years and only 10-15% of cases are located on the trunk. Radiotherapy and previous trauma have been implied as risk factors. We report the case of a 57 year-old male with an eight-month history of a hard painless erythematous-violaceous tumor on the presternal region. Histopathology evidenced a malignant spindle cell tumor, "cigar" shaped, with pleomorphic nuclei and a high mitotic index that occupied the entire dermal thickness. Immunohistochemical staining of the tumor cells was positive for smooth muscle actin, desmin and vimentin and negative for S-100 protein and pan-cytokeratin, which supported the diagnosis of dermal leiomyosarcoma. Radical surgery was performed to remove the tumor.

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Year:  2011        PMID: 22147043     DOI: 10.1590/s0365-05962011000500021

Source DB:  PubMed          Journal:  An Bras Dermatol        ISSN: 0365-0596            Impact factor:   1.896


  3 in total

1.  Primary Cutaneous Leiomyosarcoma in a Young Patient Previously Misdiagnosed as Pleomorphic Fibroma.

Authors:  Fariba Abbasi; Rahim Mahmudlu; Yasaman Nikniaz; Makan Rezaie
Journal:  Iran J Pathol       Date:  2015

Review 2.  Cutaneous leiomyosarcoma on the trunk: An unusual presentation with an aggressive course - Case report and review of literature.

Authors:  Lina Hmida; Feryel Letaief; Raoudha Doghri; Khedija Meddeb; Khalil Mahjoubi; Amina Mokrani; Yosra Yahiaoui; Azza Gabsi; Nesrine Cheraiet; Henda Rais; Mouna Ayadi; Amel Mezlini
Journal:  Pan Afr Med J       Date:  2018-11-19

3.  Cutaneous leiomyosarcoma on the face.

Authors:  Nathalia Dias Negrão Murback; Luiz C Takita; Bruna Corrêa de Castro; Gunter Hans Filho
Journal:  An Bras Dermatol       Date:  2018-03       Impact factor: 1.896

  3 in total

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