OBJECTIVES: To characterize methicillin-resistant Staphylococcus aureus (MRSA) clinical strains from cats and dogs in France, and to compare the clones identified with the distribution of French human MRSA. METHODS: Susceptibilities to antimicrobials were assessed by disc diffusion. Resistance and virulence genes were screened using a microarray-based assay. Isolates were additionally characterized by SmaI macrorestriction analysis and spa typing. RESULTS: From 2006 to 2010, the proportion of MRSA infections in pets in France was low (1.8%), but most isolates (87.0%, 20/23) belonged to human clones. The most common clones were the Lyon clone (69.6%, 16/23), the livestock-associated CC398 (13.0%, 3/23) and the Geraldine clone (8.7%, 2/23). Interestingly, we report the first USA300 clone infecting a European dog, which was probably imported by a US patient. CONCLUSIONS: Over a 5 year period, the proportion of MRSA infections in pets appears low (<2%) in France, but the distribution of the clones mostly mirrors the epidemiology of human invasive clones. These data highlight the role of pets as both victims and reservoirs of endemic, epidemic and/or invasive MRSA.
OBJECTIVES: To characterize methicillin-resistant Staphylococcus aureus (MRSA) clinical strains from cats and dogs in France, and to compare the clones identified with the distribution of French human MRSA. METHODS: Susceptibilities to antimicrobials were assessed by disc diffusion. Resistance and virulence genes were screened using a microarray-based assay. Isolates were additionally characterized by SmaI macrorestriction analysis and spa typing. RESULTS: From 2006 to 2010, the proportion of MRSA infections in pets in France was low (1.8%), but most isolates (87.0%, 20/23) belonged to human clones. The most common clones were the Lyon clone (69.6%, 16/23), the livestock-associated CC398 (13.0%, 3/23) and the Geraldine clone (8.7%, 2/23). Interestingly, we report the first USA300 clone infecting a European dog, which was probably imported by a US patient. CONCLUSIONS: Over a 5 year period, the proportion of MRSA infections in pets appears low (<2%) in France, but the distribution of the clones mostly mirrors the epidemiology of human invasive clones. These data highlight the role of pets as both victims and reservoirs of endemic, epidemic and/or invasive MRSA.
Authors: S Vincze; I Stamm; S Monecke; P A Kopp; T Semmler; L H Wieler; A Lübke-Becker; B Walther Journal: Appl Environ Microbiol Date: 2012-11-16 Impact factor: 4.792
Authors: Suzanne Hower; Matthew C Phillips; Micah Brodsky; Adrienne Dameron; Manuel A Tamargo; Norma C Salazar; Charlene R Jackson; John B Barrett; Maureen Davidson; Johnnie Davis; Sampa Mukherjee; Ruth Y Ewing; Maribeth L Gidley; Christopher D Sinigalliano; Lisa Johns; Frank E Johnson; Olufunmilola Adebanjo; Lisa R W Plano Journal: Microb Ecol Date: 2013-03-19 Impact factor: 4.552
Authors: Alejandro Dorado-García; Marian Eh Bos; Haitske Graveland; Brigitte Agl Van Cleef; Koen M Verstappen; Jan Ajw Kluytmans; Jaap A Wagenaar; Dick Jj Heederik Journal: BMJ Open Date: 2013-09-19 Impact factor: 2.692