Literature DB >> 22145918

Amine-functionalized lanthanide-doped KGdF4 nanocrystals as potential optical/magnetic multimodal bioprobes.

Qiang Ju1, Datao Tu, Yongsheng Liu, Renfu Li, Haomiao Zhu, Jincan Chen, Zhuo Chen, Mingdong Huang, Xueyuan Chen.   

Abstract

Amine-functionalized lanthanide-doped KGdF(4) nanocrystals, synthesized via a facile one-step solvothermal route by employing polyethylenimine as the surfactant and capping ligand, have been demonstrated to be sensitive time-resolved FRET bioprobes to detect a trace amount of biomolecules such as avidin at a concentration of 5.5 nM and to be potential T(1)-MRI contrast agents due to a large longitudinal relaxivity of Gd(3+) (5.86 S(-1)·mM(-1) per Gd ion and 3.99 × 10(5) S(-1)·mM(-1) per nanocrystal).
© 2011 American Chemical Society

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Year:  2011        PMID: 22145918     DOI: 10.1021/ja2102604

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  27 in total

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