Literature DB >> 22145663

Naphthoquinone-like polyketide isolated from Streptomyces sp. RI-77 and its predicted biosynthetic pathway.

Miho Izumikawa1, Ryutaro Satou, Keiichiro Motohashi, Aya Nagai, Yasuo Ohnishi, Motoki Takagi, Kazuo Shin-ya.   

Abstract

A novel naphthoquinone-like polyketide, JBIR-85 (1), with a unique skeleton and antioxidative activity was isolated from a culture of Streptomyces sp. RI-77. The planar structure of 1 was established on the basis of extensive NMR and MS analyses. The structure of 1 including the absolute configuration was established via X-ray crystallographic analysis. Since 1 exhibits a unique skeleton, we performed feeding experiments to reconfirm the structure and predict the biosynthetic pathway.

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Year:  2011        PMID： 22145663     DOI： 10.1021/np200651e

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

1.  JBIR-76 and JBIR-77, modified naphthoquinones from Streptomyces sp. RI-77.

Authors:  Keiichiro Motohashi; Miho Izumikawa; Noritaka Kagaya; Motoki Takagi; Kazuo Shin-Ya
Journal:  J Antibiot (Tokyo)       Date:  2016-01-06       Impact factor: 2.649

2.  Ti(Oi-Pr)4-promoted photoenolization Diels-Alder reaction to construct polycyclic rings and its synthetic applications.

Authors:  Baochao Yang; Kuaikuai Lin; Yingbo Shi; Shuanhu Gao
Journal:  Nat Commun       Date:  2017-09-20       Impact factor: 14.919

3.  Streptomyces-Derived Metabolites with Potential Photoprotective Properties-A Systematic Literature Review and Meta-Analysis on the Reported Chemodiversity.

Authors:  Jeysson Sánchez-Suárez; Ericsson Coy-Barrera; Luisa Villamil; Luis Díaz
Journal:  Molecules       Date:  2020-07-15       Impact factor: 4.411
  3 in total

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