BACKGROUND: The leydigioma is the most frequent interstitial neoplasm of the testis. Clinical symptoms of all leydigioma usually are isosexual precocious pseudo-puberty due to autonomous testosterone overproduction, suppressed gonadotropin levels and a testis mass. Nowadays its therapy is debated. DESIGN AND METHODS: We report a case of a young child treated in 2008 for a leydigioma of the testis with atypical clinical behavior. Testicular oncologic markers and hormonal profile were assessed. RESULTS: The patient was treated successfully with organ-confined surgery. CONCLUSION: We want to confirm the safety of conservative surgery against radical orchiectomy and review the literature of the last decade on this debated matter.
BACKGROUND: The leydigioma is the most frequent interstitial neoplasm of the testis. Clinical symptoms of all leydigioma usually are isosexual precocious pseudo-puberty due to autonomous testosterone overproduction, suppressed gonadotropin levels and a testis mass. Nowadays its therapy is debated. DESIGN AND METHODS: We report a case of a young child treated in 2008 for a leydigioma of the testis with atypical clinical behavior. Testicular oncologic markers and hormonal profile were assessed. RESULTS: The patient was treated successfully with organ-confined surgery. CONCLUSION: We want to confirm the safety of conservative surgery against radical orchiectomy and review the literature of the last decade on this debated matter.
Authors: Alberto Verrotti; Laura Penta; Letizia Zenzeri; Laura Lucchetti; Paolo Giovenali; Pierpaolo De Feo Journal: Front Pediatr Date: 2015-11-02 Impact factor: 3.418