| Literature DB >> 22143352 |
Jifu Wang1, Yung Pin Chen, Kejian Yao, Perry A Wilbon, Wujie Zhang, Lixia Ren, Juhua Zhou, Mitzi Nagarkatti, Chunpeng Wang, Fuxiang Chu, Xiaoming He, Alan W Decho, Chuanbing Tang.
Abstract
We report novel robust resin acid-derived antimicrobial agents that exhibit excellent antimicrobial activities against a broad spectrum of bacteria (6 Gram-positive and 7 Gram-negative) with selective lysis of microbial membranes over mammalian membranes. Our results indicate that hydrophobicity and unique structures of resin acids can be determining factors in dictating the antimicrobial activity. This journal is © The Royal Society of Chemistry 2012Entities:
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Year: 2011 PMID： 22143352 DOI： 10.1039/c1cc16432e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222