Literature DB >> 22142539

An expedient synthesis of honokiol and its analogues as potential neuropreventive agents.

Subhankar Tripathi1, Ming-Huan Chan, Chinpiao Chen.   

Abstract

An efficient synthesis of honokiol with Suzuki-Miyaura cross coupling obtained an overall yield of 45%. The proposed approach successfully synthesized several structurally similar alkyl, alkenyl and alkynyl analogues, seven of which showed potential neuropreventive activity against MPP(+)-induced and CHP/TBHP oxidative stress induced neuroblastoma cell death.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 22142539     DOI: 10.1016/j.bmcl.2011.11.030

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

1.  Evaluation of anti-HIF and anti-angiogenic properties of honokiol for the treatment of ocular neovascular diseases.

Authors:  Divya Teja Vavilala; V K Chaithanya Ponnaluri; Debolina Kanjilal; Mridul Mukherji
Journal:  PLoS One       Date:  2014-11-25       Impact factor: 3.240

2.  Small Molecule NF-κB Inhibitors as Immune Potentiators for Enhancement of Vaccine Adjuvants.

Authors:  Brittany A Moser; Yoseline Escalante-Buendia; Rachel C Steinhardt; Matthew G Rosenberger; Britteny J Cassaidy; Nihesh Naorem; Alfred C Chon; Minh H Nguyen; Ngoctran T Tran; Aaron P Esser-Kahn
Journal:  Front Immunol       Date:  2020-09-25       Impact factor: 7.561

3.  Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands.

Authors:  Lukas Rycek; Roshan Puthenkalam; Michael Schnürch; Margot Ernst; Marko D Mihovilovic
Journal:  Bioorg Med Chem Lett       Date:  2014-11-04       Impact factor: 2.940

4.  Synthesis of Bisphenol Neolignans Inspired by Honokiol as Antiproliferative Agents.

Authors:  Nunzio Cardullo; Vincenza Barresi; Vera Muccilli; Giorgia Spampinato; Morgana D'Amico; Daniele Filippo Condorelli; Corrado Tringali
Journal:  Molecules       Date:  2020-02-07       Impact factor: 4.411

  4 in total

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