Literature DB >> 22142051

Intraoperative hyperkaliemia complicating hand-assisted live-donor nephrectomy.

David van Dellen1, Afshin Tavakoli, Richard Wadsworth, Titus Augustine.   

Abstract

OBJECTIVES: Live donation has become increasingly valuable as a potential source of kidneys for transplant with hand-assisted laparoscopic donation is an important method of organ procurement. An important consideration is adequate preoperative and intraoperative planning, and precautions to minimize potential risks in the donor while providing a graft with good primary function.
MATERIALS AND METHODS: We present a case of live donation in which a hand-assisted laparoscopic approach was used to facilitate kidney donation. The process was complicated by a period of profound intraoperative hyperkalaemia, subsequently ascribed to rhabdomyolysis owing to muscle necrosis.
RESULTS: A 46-year-old man underwent assessment for live kidney donation for his brother. Preoperative investigations revealed normal renal function with no contraindications to donation. However, at the time of donation, a period of unexplained hyperkalaemia occurred that resolved spontaneously with fluid resuscitation and aggressive diuresis. After surgery, he was demonstrated to have an elevated creatine kinase level associated with unilateral gluteal pain and bruising. There were no long-term complications, and the donor made a full recovery with normal renal function. Hyperkalaemia was ascribed to extensive rhabdomyolysis owing to positioning on the operating table at the time of surgery.
CONCLUSIONS: Rhabdomyolysis associated with laparoscopic renal surgery requires prompt recognition and treatment while unexplained hyperkalaemia may herald its onset. It is important that an increased sense of vigilance is given to patients with increased muscularity or body mass, especially in donor nephrectomy patients, because of its effect on the remaining solitary kidney.

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Year:  2011        PMID: 22142051

Source DB:  PubMed          Journal:  Exp Clin Transplant        ISSN: 1304-0855            Impact factor:   0.945


  1 in total

1.  Sudden Intraoperative Hyperkalemia during Laparoscopic Radical Nephrectomy in a Patient with Underlying Renal Insufficiency.

Authors:  Sung Hoon Jung; Yun-Joung Han; Sang Ho Shin; Hyo Seon Lee; Ji Young Lee
Journal:  Acute Crit Care       Date:  2018-11-21
  1 in total

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