| Literature DB >> 22141731 |
Yi Zou1, Yu Hu, Hai Liu, Daqing Shi.
Abstract
An efficient one-pot synthesis of spiro[indoline-3,4'-pyrano[2,3-c]pyrazole] derivatives by four-component reaction of hydrazine, β-keto ester, isatin, and malononitrile or ethyl cyanoacetate catalyzed by piperidine under ultrasound irradiation is described. This synthesis was confirmed to follow the group-assistant-purification chemistry (GAP) chemistry process, which can avoid traditional chromatography and recrystallization purifications.Entities:
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Year: 2011 PMID: 22141731 DOI: 10.1021/co200128k
Source DB: PubMed Journal: ACS Comb Sci ISSN: 2156-8944 Impact factor: 3.784