| Literature DB >> 22139657 |
Abstract
This protocol describes a strategy for analyzing phylogenetic Y-SNPs in a hierarchical multiplex assay by utilizing the SNaPshot(®) Multiplex System. Step by step, the protocol assists in the appropriate selection of SNPs, the primer design, the set up of PCR/SBE reactions as well as in the analysis of the results. Furthermore, a forensic approach is highlighted, in which the most probable ancestry of an unknown male DNA is inferred by the geographical distribution of the assigned Y-SNP haplogroup.Mesh：
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Year: 2012 PMID： 22139657 DOI： 10.1007/978-1-61779-461-2_9
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745