Literature DB >> 22139205

[Th1, Th17 and Th1+17 cells].

H-D Chang1, T Kamradt, H Schulze-Koops.   

Abstract

T helper cells contribute to the induction and maintenance of rheumatic inflammation through the secretion of cytokines. The analysis of Th1 cells expressing interferon-γ, Th17 cells expressing interleukin-17 and the newly described Th1+17 cells could give insight into the pathophysiological mechanisms of rheumatic diseases. This could lead to the development of novel, targeted therapeutic strategies.

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Year:  2011        PMID： 22139205     DOI： 10.1007/s00393-011-0779-5

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN： 0340-1855            Impact factor:   1.372


  15 in total

1.  RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

Authors:  Laura Codarri; Gabor Gyülvészi; Vinko Tosevski; Lysann Hesske; Adriano Fontana; Laurent Magnenat; Tobias Suter; Burkhard Becher
Journal:  Nat Immunol       Date:  2011-04-24       Impact factor: 25.606

Review 2.  Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes.

Authors:  Arnaud Hot; Pierre Miossec
Journal:  Ann Rheum Dis       Date:  2011-02-22       Impact factor: 19.103

3.  T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells.

Authors:  Maryam Afkarian; John R Sedy; Jianfei Yang; Nils G Jacobson; Nezih Cereb; Soo Y Yang; Theresa L Murphy; Kenneth M Murphy
Journal:  Nat Immunol       Date:  2002-05-13       Impact factor: 25.606

4.  Microbial lipopeptides induce the production of IL-17 in Th cells.

Authors:  C Infante-Duarte; H F Horton; M C Byrne; T Kamradt
Journal:  J Immunol       Date:  2000-12-01       Impact factor: 5.422

5.  Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis.

Authors:  Jan Leipe; Markus A Schramm; Mathias Grunke; Michael Baeuerle; Claudia Dechant; Axel P Nigg; Matthias N Witt; Volker Vielhauer; Christiane S Reindl; Hendrik Schulze-Koops; Alla Skapenko
Journal:  Ann Rheum Dis       Date:  2011-05-18       Impact factor: 19.103

6.  Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis.

Authors:  Oliver Frey; Juliane Meisel; Andreas Hutloff; Kerstin Bonhagen; Lisa Bruns; Richard A Kroczek; Lars Morawietz; Thomas Kamradt
Journal:  Ann Rheum Dis       Date:  2010-05-24       Impact factor: 19.103

7.  Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice.

Authors:  David Bending; Hugo De la Peña; Marc Veldhoen; Jenny M Phillips; Catherine Uyttenhove; Brigitta Stockinger; Anne Cooke
Journal:  J Clin Invest       Date:  2009-02-02       Impact factor: 14.808

8.  Th memory for interleukin-17 expression is stable in vivo.

Authors:  Maria H Lexberg; Annegret Taubner; Anna Förster; Inka Albrecht; Anne Richter; Thomas Kamradt; Andreas Radbruch; Hyun-Dong Chang
Journal:  Eur J Immunol       Date:  2008-10       Impact factor: 5.532

Review 9.  Transcriptional regulatory networks in Th17 cell differentiation.

Authors:  Liang Zhou; Dan R Littman
Journal:  Curr Opin Immunol       Date:  2009-03-26       Impact factor: 7.486

10.  Phenotypic and functional features of human Th17 cells.

Authors:  Francesco Annunziato; Lorenzo Cosmi; Veronica Santarlasci; Laura Maggi; Francesco Liotta; Benedetta Mazzinghi; Eliana Parente; Lucia Filì; Simona Ferri; Francesca Frosali; Francesco Giudici; Paola Romagnani; Paola Parronchi; Francesco Tonelli; Enrico Maggi; Sergio Romagnani
Journal:  J Exp Med       Date:  2007-07-16       Impact factor: 14.307
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