BACKGROUND: The prevalence of tumors in the spleen is rare; most tumors are benign and of vascular origin. In 2004 a vascular lesion was first described, the sclerosing angiomatoid nodular transformation (SANT), which is a benign lesion with good circumscription and multinodular angiomatoid appearance. We report a case of this rare tumor in the spleen which was incidentally found in a patient with a tumorous lesion in the pancreatic tail. CASE REPORT: A 69-year-old patient was referred to our hospital with a tumor in the pancreatic tail which was suspicious for cancer. Radiologic work-up revealed furthermore a 4 cm in diameter large lesion central in the spleen suspicious for metastasis of the pancreatic tumor. The patient underwent surgery and a distal pancreatectomy with splenectomy was performed. Histologic specimen obtained a sclerosing angiomatoid nodular transformation in the spleen. The operative and postoperative course was uneventful. CONCLUSIONS: SANT of the spleen are very rare tumors and should be considered as an important differential diagnosis to other vascular lesions.
BACKGROUND: The prevalence of tumors in the spleen is rare; most tumors are benign and of vascular origin. In 2004 a vascular lesion was first described, the sclerosing angiomatoid nodular transformation (SANT), which is a benign lesion with good circumscription and multinodular angiomatoid appearance. We report a case of this rare tumor in the spleen which was incidentally found in a patient with a tumorous lesion in the pancreatic tail. CASE REPORT: A 69-year-old patient was referred to our hospital with a tumor in the pancreatic tail which was suspicious for cancer. Radiologic work-up revealed furthermore a 4 cm in diameter large lesion central in the spleen suspicious for metastasis of the pancreatic tumor. The patient underwent surgery and a distal pancreatectomy with splenectomy was performed. Histologic specimen obtained a sclerosing angiomatoid nodular transformation in the spleen. The operative and postoperative course was uneventful. CONCLUSIONS: SANT of the spleen are very rare tumors and should be considered as an important differential diagnosis to other vascular lesions.
Authors: Aashiyana F Koreishi; Adam J Saenz; Stephen E Fleming; Julie Teruya-Feldstein Journal: Int J Surg Pathol Date: 2009-08-10 Impact factor: 1.271
Authors: Maritza Martel; Wah Cheuk; Luciano Lombardi; Beatriz Lifschitz-Mercer; John K C Chan; Juan Rosai Journal: Am J Surg Pathol Date: 2004-10 Impact factor: 6.394
Authors: J Diebold; A Le Tourneau; B Marmey; S Prevot; H K Müller-Hermelink; H Sevestre; T Molina; C Billotet; P Gaulard; J-F Knopf; S Bendjaballah; A Mangnan-Marai; J Brière; B Fabiani; J Audouin Journal: Histopathology Date: 2008-07-16 Impact factor: 5.087