Literature DB >> 22138292

[Surgical treatment of liver metastasis in patients with colorectal cancer].

Mircea Chirica1, Mahaut Leconte, Olivier Oberlin, Bertrand Dousset.   

Abstract

Half of patients with colorectal cancer have liver metastasis during their illness. Surgical resection of metastases represents the only curative treatment with prolonged survival in more than 50 % of patients. The aim of liver resection is complete excision of the lesions with histological negative margins while preserving sufficient functional liver parenchyma. In patients with diffuse liver disease, the radiofrequency ablation of metastases may be associated with surgical resection. The use of portal vein remobilization and neoadjuvant chemotherapy can also increase the number of patients for curative treatment. Despite this progress, from 50 to 60 % of patients relapse after complete resection of MHCCR. Surgical treatment of recurrent aggressive and effective chemotherapy allows the prolonged survival of these patients. The modern treatment of liver metastasis of colorectal cancers can be envisaged as part of a multidisciplinary approach to increase the number of patients for curative treatment.
Copyright © 2011 Elsevier Masson SAS. All rights reserved.

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Year:  2011        PMID: 22138292     DOI: 10.1016/j.lpm.2011.10.009

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  4 in total

1.  Mouse models for colorectal cancer.

Authors:  Baktiar O Karim; David L Huso
Journal:  Am J Cancer Res       Date:  2013-06-20       Impact factor: 6.166

2.  Key genes and regulatory networks involved in the initiation, progression and invasion of colorectal cancer.

Authors:  Matin Asghari; Mohammad Foad Abazari; Hanieh Bokharaei; Maryam Nouri Aleagha; Vahdat Poortahmasebi; Hassan Askari; Sepehr Torabinejad; Abbas Ardalan; Navid Negaresh; Atousa Ataei; Parisa Pazooki; Mansour Poorebrahim
Journal:  Future Sci OA       Date:  2018-01-24

3.  Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice.

Authors:  Ahmed Hammad; Zhao-Hong Zheng; Akhileshwar Namani; Mohamed Elshaer; Xiu Jun Wang; Xiuwen Tang
Journal:  BMC Cancer       Date:  2021-05-25       Impact factor: 4.430

4.  Interleukin-12 prevents colorectal cancer liver metastases in mice.

Authors:  Fei Shen; Jiang-Lin Li; Weng-Song Cai; Guang-Hui Zhu; Wei-Li Gu; Lin Jia; Bo Xu
Journal:  Onco Targets Ther       Date:  2013-05-13       Impact factor: 4.147

  4 in total

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