Literature DB >> 22135601

The Socio-Demographic and Clinical Factors Associated with Quality of Life among Patients with Haematological Cancer in a Large Government Hospital in Malaysia.

Das Priscilla1, Awang Hamidin, Md Zain Azhar, Kon Noorjan, Md Said Salmiah, Khalid Bahariah.   

Abstract

BACKGROUND: The paper examined the quality of life of haematological cancer patients according to their socio-demographic profiles and clinical diagnoses.
METHODS: This cross-sectional study was conducted at the tertiary referral centre of Ampang Hospital, Kuala Lumpur, involving 105 patients. The European Organisation for Research and Treatment of Cancer Quality of Life (EORTC QLQ-C30) questionnaire was used to measure their quality of life.
RESULTS: The study involved patients diagnosed with all types of haematological cancer, including non-Hodgkin lymphoma (NHL), acute myelogenous leukaemia (AML), acute lymphoblastic leukaemia (ALL), Hodgkin lymphoma (HL), and multiple myeloma (MM), with a response rate of 83.3%. The patients with ALL, HL, without NHL, and without MM were younger than other patients. There were significant differences in quality of life scores in different socio-demographic groups and types of cancer diagnosis. The global quality of life of the female patients was much better than that of the male patients. Patients who were 40 years old or younger had a better global quality of life and physical functioning, as well as fewer symptoms of constipation, nausea, and vomiting. Employed patients were in less pain but showed greater impairments of cognitive function than did unemployed patients. Patients who earned a monthly wage of RM1000 or less had reduced physical function, more symptoms of pain, and more financial difficulties compared with patients who earned more. Patients with AML tended to have better physical functioning than did patients with MM, whose physical functioning was impaired. Comparatively, more symptoms of dyspnoea were found in ALL and HL patients than in other types of lymphoma. Compared with other patients, those with ALL had a greater loss of appetite, and other lymphoma patients had fewer symptoms of pain. Patients with NHL had impaired role functioning and more constipation compared with other patients. The results were all statistically significant (P < 0.05).
CONCLUSION: The quality of life of haematological cancer patients is affected by socio-demographic factors and clinical diagnoses. Efforts should be made to improve the overall quality of life of these patients.

Entities:  

Keywords:  haematological malignancies; leukaemia; lymphoma; multiple myeloma; oncology; quality of life; socioeconomic factors

Year:  2011        PMID: 22135601      PMCID: PMC3216227     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN: 1394-195X


  9 in total

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Review 2.  Overview of cancer in Malaysia.

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Authors:  Shabbir M H Alibhai; Marc Leach; Husnain Kermalli; Vikas Gupta; Matthew E Kowgier; George A Tomlinson; Joseph Brandwein; Rena Buckstein; Mark D Minden
Journal:  Crit Rev Oncol Hematol       Date:  2007-08-31       Impact factor: 6.312

4.  Psychosocial adaptation and quality of life among Brazilian patients with different hematological malignancies.

Authors:  Fábio R M Santos; Elisa H Kozasa; Maria de Lourdes L F Chauffaille; Gisele W B Colleoni; Jose Roberto Leite
Journal:  J Psychosom Res       Date:  2006-05       Impact factor: 3.006

5.  The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology.

Authors:  N K Aaronson; S Ahmedzai; B Bergman; M Bullinger; A Cull; N J Duez; A Filiberti; H Flechtner; S B Fleishman; J C de Haes
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7.  Battling the hematological malignancies: the 200 years' war.

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8.  Health related quality of life in a nationally representative sample of haematological patients.

Authors:  Anna T Johnsen; Dorte Tholstrup; Morten Aa Petersen; Lise Pedersen; Mogens Groenvold
Journal:  Eur J Haematol       Date:  2009-03-05       Impact factor: 2.997

9.  Work ability and return-to-work in cancer patients.

Authors:  A G E M de Boer; J H A M Verbeek; E R Spelten; A L J Uitterhoeve; A C Ansink; T M de Reijke; M Kammeijer; M A G Sprangers; F J H van Dijk
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  9 in total
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2.  Quality of life amongst lymphoma survivors in a developing country.

Authors:  Diana L C Ng; Y C Leong; Gin Gin Gan
Journal:  Support Care Cancer       Date:  2016-07-26       Impact factor: 3.603

Review 3.  Optimizing Quality of Care and Patient Safety in Malaysia: The Current Global Initiatives, Gaps and Suggested Solutions.

Authors:  Mu'taman Jarrar; Hamzah Abdul Rahman; Mohammad Sobri Don
Journal:  Glob J Health Sci       Date:  2015-10-20

4.  Health-related quality of life of patients with multiple myeloma: A real-world study in China.

Authors:  Xiaozhe Li; Junru Liu; Meilan Chen; Jingli Gu; Beihui Huang; Dong Zheng; Juan Li
Journal:  Cancer Med       Date:  2020-09-02       Impact factor: 4.452

  4 in total

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