Literature DB >> 22135574

Factors affecting the outcomes in children post-myelomeningocoele repair in northeastern peninsular malaysia.

Badrisyah Idris1.   

Abstract

BACKGROUND: The present study aimed to evaluate the impact of multiple factors and outcomes (ambulatory function and sphincter function) on children with myelomeningocoele (MMC) following surgical repair.
METHOD: A retrospective chart review of children that underwent surgery for MMC in the Hospital Universiti Sains Malaysia from 1 January 1990 to 31 December 2004 was conducted. Only those children who were followed-up for at least 18 months after the operation were included in the study.
RESULTS: A total of 42 children with MMC were included in the study. Approximately 79% of the MMC were located in the lumbosacral and sacral regions. Thirty (71.4%) of the children had hydrocephalus, and 28 (67.7%) had a cerebrospinal fluid (CSF) shunt inserted. An analysis of the association between the predictors of ambulatory status revealed that hydrocephalus (P = 0.013), the presence of a CSF shunt (P = 0.005), intact motor function at L3 and below (P < 0.001), and the presence of deep tendon reflexes (P < 0.001) were good factors of ambulatory status. Only 16.7% of the children did not have urinary or faecal incontinence. Hydrocephalus (P = 0.049) and low-level MMC (P = 0.028) were significantly associated with sphincter control.
CONCLUSION: Multiple factors contributed to the outcomes in post-MMC repair children in terms of ambulation and sphincter function following a repair of MMC. The Spina Bifida Neurological Scale (SBNS) should be applied during the management of these children to identify neurological deterioration.

Entities:  

Keywords:  children; myelomeningocoele; neural tube defects; neurosurgery; spina bifida; spinal cord

Year:  2011        PMID: 22135574      PMCID: PMC3216194     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN: 1394-195X


  29 in total

1.  Ambulation in adults with myelomeningocele. Is it possible to predict the level of ambulation in early life?

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2.  Age-related walking in children with spina bifida.

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3.  Can prenatal ultrasound findings predict ambulatory status in fetuses with open spina bifida?

Authors:  J R Biggio; J Owen; K D Wenstrom; W J Oakes
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4.  Comparison of simultaneous versus delayed ventriculoperitoneal shunt insertion in children undergoing myelomeningocele repair.

Authors:  P D Miller; I F Pollack; D Pang; A L Albright
Journal:  J Child Neurol       Date:  1996-09       Impact factor: 1.987

5.  Ambulation in patients with myelomeningocele: a multivariate statistical analysis.

Authors:  L Samuelsson; M Skoog
Journal:  J Pediatr Orthop       Date:  1988 Sep-Oct       Impact factor: 2.324

6.  Wound closure of the myelomeningocoele defect.

Authors:  E A Luce; J Walsh
Journal:  Plast Reconstr Surg       Date:  1985-03       Impact factor: 4.730

Review 7.  Care of the neonate with a myelomeningocele.

Authors:  D G McLone
Journal:  Neurosurg Clin N Am       Date:  1998-01       Impact factor: 2.509

8.  A proposed grading and scoring system for spina bifida: Spina Bifida Neurological Scale (SBNS)

Authors:  S Oi; S Matsumoto
Journal:  Childs Nerv Syst       Date:  1992-09       Impact factor: 1.475

Review 9.  Epidemiology of neural tube defects.

Authors:  Lauren Frey; W Allen Hauser
Journal:  Epilepsia       Date:  2003       Impact factor: 5.864

10.  Cesarean section before the onset of labor and subsequent motor function in infants with meningomyelocele diagnosed antenatally.

Authors:  D A Luthy; T Wardinsky; D B Shurtleff; K A Hollenbach; D E Hickok; D A Nyberg; T J Benedetti
Journal:  N Engl J Med       Date:  1991-03-07       Impact factor: 91.245

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  2 in total

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Authors:  Anne C Tita; John R Frampton; Christian Roehmer; Sara E Izzo; Amy J Houtrow; Brad E Dicianno
Journal:  Am J Phys Med Rehabil       Date:  2019-12       Impact factor: 2.159

2.  Establishing Content Validity Evidence of the Pittsburgh Impairment Testing Tool (PITT) for Adults With Spina Bifida.

Authors:  Alan Cuevas Villagomez; Gina McKernan; Amy J Houtrow; Brad E Dicianno
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  2 in total

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