Literature DB >> 22135520

HIV- and AIDS-related Ocular Manifestations in Tanzanian Patients.

Soumendra Sahoo1.   

Abstract

BACKGROUND: Although around 70% of HIV+ cases used to have ocular manifestations, the late reporting of cases often results in severe forms of ocular morbidity that would otherwise have been prevented. The objective of this study was to describe the ocular manifestations of HIV and AIDS-related patients who had been admitted to TM Jafferji Hospital, Dar-es-Salaam, Tanzania.
METHODS: Proven cases of HIV were recruited in this study. Detailed slit lamp examination and fundoscopy using a +90D lens were carried out in all cases after thoroughly dilating the pupil with 1% Tropicamide eye drops.
RESULTS: Around 90% of the recruited cases were in clinical stage III and IV HIV. The notable ocular manifestations included micro-vasculopathy of the retina in 25%, uveitis in 8%, CMV retinitis in 7%, neuro-ophthalmic manifestation in 6%, Herpes zoster ophthalmicus in 5%, Kaposi's sarcoma in 3% and conjunctival carcinoma in 2% of cases. Fifty-three percent of the cases had other anterior segment disorders like conjunctivitis, blepharitis and corneal ulcers.
CONCLUSION: Most of the cases recruited in our study were in the late stages of HIV. A significantly high number of cases (70%) had ocular manifestations. Around 53% had additional anterior segment disorders like conjunctivitis, blepharitis and corneal ulcers.

Entities:  

Keywords:  AIDS; CMV retinitis; HIV; medical sciences; micro-vasculopathy

Year:  2010        PMID: 22135520      PMCID: PMC3216149     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN: 1394-195X


  11 in total

1.  Ocular lesions associated with HIV infection in India: a series of 100 consecutive patients evaluated at a referral center.

Authors:  J Biswas; H N Madhavan; A E George; N Kumarasamy; S Solomon
Journal:  Am J Ophthalmol       Date:  2000-01       Impact factor: 5.258

Review 2.  Ocular manifestations of HIV infection.

Authors:  E T Cunningham; T P Margolis
Journal:  N Engl J Med       Date:  1998-07-23       Impact factor: 91.245

3.  The epidemiology of CMV retinitis in Africa.

Authors:  P Kestelyn
Journal:  Ocul Immunol Inflamm       Date:  1999-12       Impact factor: 3.070

4.  Herpes zoster ophthalmicus in Malawi.

Authors:  S Lewallen
Journal:  Ophthalmology       Date:  1994-11       Impact factor: 12.079

5.  AIDS related eye disease in Burundi, Africa.

Authors:  I Cochereau; N Mlika-Cabanne; P Godinaud; T Niyongabo; B Poste; A Ngayiragije; M C Dazza; P Aubry; B Larouzé
Journal:  Br J Ophthalmol       Date:  1999-03       Impact factor: 4.638

Review 6.  HIV/AIDS and blindness.

Authors:  P G Kestelyn; E T Cunningham
Journal:  Bull World Health Organ       Date:  2001       Impact factor: 9.408

7.  Ocular disease in patients with tuberculosis and HIV presenting with fever in Africa.

Authors:  N A V Beare; J G Kublin; D K Lewis; M J Schijffelen; R P H Peters; G Joaki; J Kumwenda; E E Zijlstra
Journal:  Br J Ophthalmol       Date:  2002-10       Impact factor: 4.638

8.  Evaluation of ocular manifestations and blindness in HIV/AIDS patients on HAART in a tertiary care hospital in western India.

Authors:  S U Shah; S P Kerkar; A R Pazare
Journal:  Br J Ophthalmol       Date:  2008-10-24       Impact factor: 4.638

9.  Ophthalmic manifestations of HIV infections in India in the era of HAART: analysis of 100 consecutive patients evaluated at a tertiary eye care center in India.

Authors:  Sujit Gharai; Pradeep Venkatesh; Satpal Garg; S K Sharma; Rajpal Vohra
Journal:  Ophthalmic Epidemiol       Date:  2008 Jul-Aug       Impact factor: 1.648

10.  [Ocular manifestations of AIDS in Dakar].

Authors:  N B Ndoye; P S Sow; E A Ba; M R Ndiaye; A Wade; A M Coll-Seck
Journal:  Dakar Med       Date:  1993
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  2 in total

1.  Ocular manifestation and their associated factors among HIV/AIDS patients receiving highly active antiretroviral therapy in Southern Ethiopia.

Authors:  Anteneh Amsalu; Kindie Desta; Demiss Nigussie; Demoze Delelegne
Journal:  Int J Ophthalmol       Date:  2017-05-18       Impact factor: 1.779

2.  Retinal Microvasculopathy Is Common in HIV/AIDS Patients: A Cross-Sectional Study at the Cape Coast Teaching Hospital, Ghana.

Authors:  Emmanuel Kwasi Abu; Samuel Abokyi; Dorcas Obiri-Yeboah; Richard Kobina Dadzie Ephraim; Daniel Afedo; Lawrence Duah Agyeman; Samuel Bert Boadi-Kusi
Journal:  J Ophthalmol       Date:  2016-12-29       Impact factor: 1.909

  2 in total

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