Literature DB >> 22132253

Real data examples in statistical methods papers: Tremendously valuable, and also tremendously misvalued.

K Y Williams1, Yun Joo Yoo, Amit Patki, David B Allison.   

Abstract

When a statistical methods paper is submitted to a journal for publication, examples in which the method is applied to real data are highly encouraged by many journals and in some cases are explicitly demanded. In this commentary, we argue that real data examples serve several useful purposes. However, we also argue that in many cases, particularly in the fields of genetics and genomics, there is an implicit or explicit expectation for examples to support purposes for which they are ill-suited and furthermore that these inappropriate expectations have negative consequences for the field. We conclude by noting that real data examples can be tremendously valuable and should continue to be used where appropriate, but that the demands for, expectations of, and conclusions drawn from them need to be scaled back.

Entities:  

Year:  2011        PMID: 22132253      PMCID: PMC3225256          DOI: 10.4310/sii.2011.v4.n3.a1

Source DB:  PubMed          Journal:  Stat Interface        ISSN: 1938-7989            Impact factor:   0.582


  8 in total

1.  The emperor's new methods.

Authors:  M Anne Spence; David A Greenberg; Susan E Hodge; Veronica J Vieland
Journal:  Am J Hum Genet       Date:  2003-04-18       Impact factor: 11.025

2.  A modified revisited Haseman-Elston method to further improve power.

Authors:  Tao Wang; Robert C Elston
Journal:  Hum Hered       Date:  2004       Impact factor: 0.444

3.  Towards sound epistemological foundations of statistical methods for high-dimensional biology.

Authors:  Tapan Mehta; Murat Tanik; David B Allison
Journal:  Nat Genet       Date:  2004-09       Impact factor: 38.330

4.  Multilocus association mapping using variable-length Markov chains.

Authors:  Sharon R Browning
Journal:  Am J Hum Genet       Date:  2006-04-07       Impact factor: 11.025

5.  Epistemological issues in omics and high-dimensional biology: give the people what they want.

Authors:  Tapan S Mehta; Stanislav O Zakharkin; Gary L Gadbury; David B Allison
Journal:  Physiol Genomics       Date:  2006-09-12       Impact factor: 3.107

6.  Testing association in the presence of linkage using the GRE and multiple markers.

Authors:  Gudrun Jonasdottir; Tim Becker; Keith Humphreys; Juni Palmgren
Journal:  Genet Epidemiol       Date:  2008-07       Impact factor: 2.135

7.  The investigation of linkage between a quantitative trait and a marker locus.

Authors:  J K Haseman; R C Elston
Journal:  Behav Genet       Date:  1972-03       Impact factor: 2.805

8.  Testing association between disease and multiple SNPs in a candidate gene.

Authors:  W James Gauderman; Cassandra Murcray; Frank Gilliland; David V Conti
Journal:  Genet Epidemiol       Date:  2007-07       Impact factor: 2.135

  8 in total
  1 in total

1.  Advantages of percent weight loss as a method of reporting weight loss after Roux-en-Y gastric bypass.

Authors:  Ida J Hatoum; Lee M Kaplan
Journal:  Obesity (Silver Spring)       Date:  2013-05-13       Impact factor: 5.002

  1 in total

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