Literature DB >> 22130906

Osteoporotic vertebral fractures: current concepts of conservative care.

Umile Giuseppe Longo1, Mattia Loppini, Luca Denaro, Nicola Maffulli, Vincenzo Denaro.   

Abstract

INTRODUCTION: Osteoporotic vertebral compression fractures (VCFs) are a growing public health problem with important socio-economic effects in western countries. In the USA, 10 million people over 50 suffer from osteoporosis. In these patients, 1.5 million annual fractures have been registered, and 50% of these are vertebral compression. SOURCES OF DATA: We performed a comprehensive search of PubMed, Medline, Cochrane, CINAHL and Embase databases using various combinations of the keywords 'osteoporosis', 'vertebral compression fractures', 'brace', 'bracing', 'orthosis', 'conservative management' and 'rehabilitation' over the years 1966-2011. All articles relevant to the subject were retrieved, and their bibliographies were hand searched for further references in the context of conservative management of osteoporotic vertebral fractures. AREAS OF AGREEMENT: Conservative management for patients with osteoporotic vertebral fractures includes bed rest, pain medication, physiotherapy and bracing. AREAS OF CONTROVERSY: A conservative management for patients with osteoporotic VCFs s has not been standardized. The utility of vertebral augmentation techniques has been questioned by recent randomized controlled trials. GROWING POINTS: Randomized controlled trials are being performed worldwide on vertebral augmentation techniques. AREAS TIMELY FOR DEVELOPING RESEARCH: Although spinal orthoses are commonly used for the management of patients with osteoporotic vertebral fractures, in the literature there is only one randomized controlled trial on bracing for this condition. While the best conservative management for subjects with osteoporotic VCFs s is not defined and standardized, no conclusions on the superiority of vertebral augmentation techniques over conservative management can be drawn.

Entities:  

Mesh:

Year:  2011        PMID: 22130906     DOI: 10.1093/bmb/ldr048

Source DB:  PubMed          Journal:  Br Med Bull        ISSN: 0007-1420            Impact factor:   4.291


  28 in total

1.  Comparative study on the period of absolute bed rest of vertebral compression fracture.

Authors:  Kyung Han Cha; Tack Geun Cho; Chang Hyun Kim; Ho Kook Lee; Jae Gon Moon
Journal:  Korean J Spine       Date:  2013-09-30

2.  Osteoporotic vertebral fractures: predictive factors for conservative treatment failure. A systematic review.

Authors:  Marco Muratore; Andrea Ferrera; Alessandro Masse; Alessandro Bistolfi
Journal:  Eur Spine J       Date:  2017-10-13       Impact factor: 3.134

3.  In vivo tricalcium phosphate, bone morphogenetic protein and autologous bone marrow biomechanical enhancement in vertebral fractures in a porcine model.

Authors:  Elena Manrique; David Chaparro; Juan Luis Cebrián; Luis López-Durán
Journal:  Int Orthop       Date:  2014-06-07       Impact factor: 3.075

4.  A 3D finite element model of prophylactic vertebroplasty in the metastatic spine: Vertebral stability and stress distribution on adjacent vertebrae.

Authors:  Alessandra Berton; Giuseppe Salvatore; Hugo Giambini; Mauro Ciuffreda; Umile Giuseppe Longo; Vincenzo Denaro; Andrew Thoreson; Kai-Nan An
Journal:  J Spinal Cord Med       Date:  2018-02-15       Impact factor: 1.985

Review 5.  Pharmacological options for pain control in patients with vertebral fragility fractures.

Authors:  Nuttan Kantilal Tanna; Terence Ong
Journal:  Osteoporos Sarcopenia       Date:  2022-10-03

6.  Three generations of treatments for osteoporotic vertebral fractures: what is the evidence?

Authors:  Luigi Aurelio Nasto; Eugenio Jannelli; Valerio Cipolloni; Luca Piccone; Alessandro Cattolico; Alessandro Santagada; Charlotte Pripp; Alfredo Schiavone Panni; Enrico Pola
Journal:  Orthop Rev (Pavia)       Date:  2022-10-13

Review 7.  Non-surgical management of acute osteoporotic vertebral compression fracture: A review.

Authors:  Bhavuk Garg; Vivek Dixit; Sahil Batra; Rajesh Malhotra; Alok Sharan
Journal:  J Clin Orthop Trauma       Date:  2017-02-07

8.  Changes in magnetic resonance imaging signal intensity in predicting complications during acute phase osteoporotic vertebral fractures.

Authors:  Keiichiro Iida; Hiromi Kumamaru; Takeyuki Saito; Katsumi Harimaya
Journal:  J Orthop       Date:  2020-06-04

9.  Incidence and Risk Factors for Complications and Mortality After Vertebroplasty or Kyphoplasty in the Osteoporotic Vertebral Compression Fracture-Analysis of 1,932 Cases From the American College of Surgeons National Surgical Quality Improvement.

Authors:  Ho-Joong Kim; Scott L Zuckerman; Meghan Cerpa; Jin S Yeom; Ronald A Lehman; Lawrence G Lenke
Journal:  Global Spine J       Date:  2020-12-30

10.  The Role of Spinal Orthoses in Osteoporotic Vertebral Fractures of the Elderly Population (Age 60 Years or Older): Systematic Review.

Authors:  Barry Ting Sheen Kweh; Hui Qing Lee; Terence Tan; Joost Rutges; Travis Marion; Kim Siong Tew; Vikram Bhalla; Shyaman Menon; Fetullah Cumhur Oner; Charles Fisher; Jin Wee Tee
Journal:  Global Spine J       Date:  2020-09-29
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