Literature DB >> 22130872

Strategies to explore functional genomics data sets in NCBI's GEO database.

Stephen E Wilhite1, Tanya Barrett.   

Abstract

The Gene Expression Omnibus (GEO) database is a major repository that stores high-throughput functional genomics data sets that are generated using both microarray-based and sequence-based technologies. Data sets are submitted to GEO primarily by researchers who are publishing their results in journals that require original data to be made freely available for review and analysis. In addition to serving as a public archive for these data, GEO has a suite of tools that allow users to identify, analyze, and visualize data relevant to their specific interests. These tools include sample comparison applications, gene expression profile charts, data set clusters, genome browser tracks, and a powerful search engine that enables users to construct complex queries.

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Year:  2012        PMID: 22130872      PMCID: PMC3341798          DOI: 10.1007/978-1-61779-400-1_3

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


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Authors:  Eric W Sayers; Tanya Barrett; Dennis A Benson; Stephen H Bryant; Kathi Canese; Vyacheslav Chetvernin; Deanna M Church; Michael DiCuccio; Ron Edgar; Scott Federhen; Michael Feolo; Lewis Y Geer; Wolfgang Helmberg; Yuri Kapustin; David Landsman; David J Lipman; Thomas L Madden; Donna R Maglott; Vadim Miller; Ilene Mizrachi; James Ostell; Kim D Pruitt; Gregory D Schuler; Edwin Sequeira; Stephen T Sherry; Martin Shumway; Karl Sirotkin; Alexandre Souvorov; Grigory Starchenko; Tatiana A Tatusova; Lukas Wagner; Eugene Yaschenko; Jian Ye
Journal:  Nucleic Acids Res       Date:  2008-10-21       Impact factor: 16.971

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