| Literature DB >> 22130705 |
Jeffrey I Zwicker1, Romaric Lacroix, Françoise Dignat-George, Barbara C Furie, Bruce Furie.
Abstract
Platelet microparticles are submicron vesicles that can support thrombin generation on externalized negatively charged phospholipids. Increased numbers of circulating platelet microparticles have been investigated as the basis of hypercoagulability in a variety of prothrombotic conditions. Measurement of platelet microparticles is not standardized and a number of preanalytic considerations can influence accurate analysis. We describe methodology for light scatter-based flow cytometry as well as impedance-based flow cytometry for the enumeration and characterization of platelet microparticles.Entities:
Mesh:
Year: 2012 PMID: 22130705 DOI: 10.1007/978-1-61779-307-3_10
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745