| Literature DB >> 22130703 |
Katherine L Tucker1, Tanya Sage, Jonathan M Gibbins.
Abstract
The study of clot retraction in vitro has been adopted as a simple and reproducible approach to assess platelet function. Plasma clots should retract away from the sides of a glass tube within a few hours allowing the rapid characterization of outside-in signaling through platelet integrin α(IIb)β(3). In this chapter, we describe the role of platelets in fibrin clot retraction and provide a detailed description of the methods used to assess this process.Entities:
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Year: 2012 PMID： 22130703 PMCID： PMC6446996 DOI： 10.1007/978-1-61779-307-3_8
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745