Literature DB >> 22129750

Inhibition of F-box protein FBXO6 gene expression by RNA interference enhances cadmium toxicity in HEK293 cells.

Gi-Wook Hwang1, Ke Du, Tsutomu Takahashi, Akira Naganuma.   

Abstract

Cadmium is a typical environmental pollutant and the causative agent of itai-itai disease. Ubiquitin ligases potentially involved in mediating the effects of cadmium toxicity were investigated by RNA interference using a panel of small inhibitory (si)RNAs. The results demonstrated that the inhibition of gene expression of FBXO6 sensitizes HEK293 cells to cadmium.

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Year:  2011        PMID: 22129750     DOI: 10.2131/jts.36.847

Source DB:  PubMed          Journal:  J Toxicol Sci        ISSN: 0388-1350            Impact factor:   2.196


  1 in total

1.  Systemic bioinformatics analysis of recurrent aphthous stomatitis gene expression profiles.

Authors:  Jian Wu; Zheng-Ping Chen; An-Quan Shang; Wei-Wei Wang; Zong-Ning Chen; Yun-Juan Tao; Yue Zhou; Wan-Xiang Wang
Journal:  Oncotarget       Date:  2017-11-10
  1 in total

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