Literature DB >> 22127835

Association between severity of dysphagia and survival in patients with head and neck cancer.

Samantha E Shune1, Lucy Hynds Karnell, Michael P Karnell, Douglas J Van Daele, Gerry F Funk.   

Abstract

BACKGROUND: This study examined risk factors for dysphagia, a common and serious condition in patients with head and neck cancer, and the association between severity of dysphagia and survival.
METHODS: Chart reviews were performed on patients diagnosed with head and neck cancer between January 2001 and April 2003, who had dysphagia diagnoses or swallowing evaluations. Regression analyses determined factors associated with dysphagia and the association between observed survival and severity of dysphagia.
RESULTS: Almost 50% of the 407 patients had dysphagia. Risk factors included advanced stage, older age, female sex, and hypopharyngeal tumors. The most severe dysphagia ([L.] nil per os or "nothing by mouth" status), which was associated with lower survival rates, was the strongest independent predictor of survival.
CONCLUSIONS: Swallowing problems should be considered when determining appropriate cancer-directed treatment and posttreatment care. Because of dysphagia's high incidence rate and association with survival, a speech-language pathologist should be involved to ensure routine diagnostic and therapeutic swallowing interventions.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID: 22127835      PMCID: PMC4304637          DOI: 10.1002/hed.21819

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  25 in total

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2.  Quality of life and oral function following radiotherapy for head and neck cancer.

Authors:  J B Epstein; S Emerton; D A Kolbinson; N D Le; N Phillips; P Stevenson-Moore; D Osoba
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4.  Impact of swallowing therapy on aspiration rate following treatment for locally advanced head and neck cancer.

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5.  Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy.

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6.  The impact of nutritional status on the prognoses of patients with advanced head and neck cancer.

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Review 9.  Dysphagia following head and neck cancer surgery.

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2.  Correlation of Patient- and Physician-Scored Dysphagia with Videofluoroscopies in Patients Treated with Radiotherapy for Head and Neck Cancer.

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3.  Clinical factors impacting on late dysphagia following radiotherapy in patients with head and neck cancer.

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4.  Analysis of dysphagia in advanced-stage head-and-neck cancer patients: impact on quality of life and development of a preventive swallowing treatment.

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6.  Swallowing Outcomes in Elderly Patients following Microvascular Reconstruction of the Head and Neck.

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Review 9.  Intersecting Mechanisms of Hypoxia and Prostaglandin E2-Mediated Inflammation in the Comparative Biology of Oral Squamous Cell Carcinoma.

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Review 10.  Dysphagia in Head and Neck Cancer Patients: Pretreatment Evaluation, Predictive Factors, and Assessment during Radio-Chemotherapy, Recommendations.

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