Literature DB >> 22127638

First cascade Mitsunobu reactions for the synthesis of 2-benzoxazole-N-phenyl and 2-benzimidazole-N-phenyl derivatives.

Yu Yan1, Qifei Zhong, Nan Zhao, Gang Liu.   

Abstract

An efficient method has been developed via cascade Mitsunobu reactions to synthesize 2-benzoxazole-N-phenyl and 2-benzimidazole-N-phenyl derivatives, which are common structural motifs in medicinal chemistry. This method also provides a new application of the Mitsunobu reaction.

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Year:  2011        PMID： 22127638     DOI： 10.1007/s11030-011-9343-0

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  11 in total

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