Literature DB >> 22125769

Health risks assessment in children for phthalate exposure associated with childcare facilities and indoor playgrounds.

Ho-Hyun Kim1, Ji-Yeon Yang, Sun-Duk Kim, Su-Hee Yang, Chung-Soo Lee, Dong-Chun Shin, Young-Wook Lim.   

Abstract

OBJECTIVES: This study assessed the health risks for children exposed to phthalate through several pathways including house dust, surface wipes and hand wipes in child facilities and indoor playgrounds.
METHODS: The indoor samples were collected from various children's facilities (40 playrooms, 42 daycare centers, 44 kindergartens, and 42 indoor-playgrounds) in both summer (Jul-Sep, 2007) and winter (Jan-Feb, 2008). Hazard index (HI) was estimated for the non-carcinogens and the examined phthalates were diethylhexyl phthalate (DEHP), diethyl phthalate (DEP), dibutyl-n-butyl phthalate (DnBP), and butylbenzyl phthalate (BBzP). The present study examined these four kinds of samples, i.e., indoor dust, surface wipes of product and hand wipes.
RESULTS: Among the phthalates, the detection rates of DEHP were 98% in dust samples, 100% in surface wipe samples, and 95% in hand wipe samples. In this study, phthalate levels obtained from floor dust, product surface and children's hand wipe samples were similar to or slightly less compared to previous studies. The 50(th) and 95(th) percentile value of child-sensitive materials did not exceed 1 (HI) for all subjects in all facilities.
CONCLUSIONS: For DEHP, DnBP and BBzP their detection rates through multi-routes were high and their risk based on health risk assessment was also observed to be acceptable. This study suggested that ingestion and dermal exposure could be the most important pathway of phthalates besides digestion through food.

Entities:  

Keywords:  Childcare facilities; Health risk assessment; Multi-route exposure; Phthalate

Year:  2011        PMID: 22125769      PMCID: PMC3214980          DOI: 10.5620/eht.2011.26.e2011008

Source DB:  PubMed          Journal:  Environ Health Toxicol        ISSN: 2233-6567


  21 in total

1.  Chronic oral toxicity of di-(2-ethylhexyl) phthalate of rats, guinea pigs, and dogs.

Authors:  C P CARPENTER; C S WEIL; H F SMYTH
Journal:  AMA Arch Ind Hyg Occup Med       Date:  1953-09

Review 2.  Monitoring phthalate exposure in humans.

Authors:  Giuseppe Latini
Journal:  Clin Chim Acta       Date:  2005-11       Impact factor: 3.786

3.  Contribution of children's activities to lead contamination of food.

Authors:  N C Freeman; L Sheldon; M Jimenez; L Melnyk; E Pellizzari; M Berry
Journal:  J Expo Anal Environ Epidemiol       Date:  2001 Sep-Oct

4.  Evaluation and analysis of exposure levels of di(2-ethylhexyl) phthalate from blood bags.

Authors:  Koichi Inoue; Migaku Kawaguchi; Retsuji Yamanaka; Tae Higuchi; Rie Ito; Koichi Saito; Hiroyuki Nakazawa
Journal:  Clin Chim Acta       Date:  2005-08       Impact factor: 3.786

5.  New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP.

Authors:  Holger M Koch; Hermann M Bolt; Ralf Preuss; Jürgen Angerer
Journal:  Arch Toxicol       Date:  2005-02-08       Impact factor: 5.153

6.  Occurrence of phthalates and musk fragrances in indoor air and dust from apartments and kindergartens in Berlin (Germany).

Authors:  H Fromme; T Lahrz; M Piloty; H Gebhart; A Oddoy; H Rüden
Journal:  Indoor Air       Date:  2004-06       Impact factor: 5.770

7.  Internal exposure of nursery-school children and their parents and teachers to di(2-ethylhexyl)phthalate (DEHP).

Authors:  Holger M Koch; Hans Drexler; Jürgen Angerer
Journal:  Int J Hyg Environ Health       Date:  2004-01       Impact factor: 5.840

8.  Frequency of mouthing behavior in young children.

Authors:  Nicolle S Tulve; Jack C Suggs; Thomas McCurdy; Elaine A Cohen Hubal; Jacqueline Moya
Journal:  J Expo Anal Environ Epidemiol       Date:  2002-07

9.  Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway.

Authors:  J J Jaakkola; L Oie; P Nafstad; G Botten; S O Samuelsen; P Magnus
Journal:  Am J Public Health       Date:  1999-02       Impact factor: 9.308

10.  Phthalates in indoor dust and their association with building characteristics.

Authors:  Carl-Gustaf Bornehag; Björn Lundgren; Charles J Weschler; Torben Sigsgaard; Linda Hagerhed-Engman; Jan Sundell
Journal:  Environ Health Perspect       Date:  2005-10       Impact factor: 9.031

View more
  6 in total

1.  Experimental estimation of migration and transfer of organic substances from consumer articles to cotton wipes: Evaluation of underlying mechanisms.

Authors:  Per Axel Clausen; Suzanne Spaan; Derk H Brouwer; Hans Marquart; Maaike le Feber; Roel Engel; Lieve Geerts; Keld Alstrup Jensen; Vivi Kofoed-Sørensen; Brian Hansen; Katleen De Brouwere
Journal:  J Expo Sci Environ Epidemiol       Date:  2015-05-20       Impact factor: 5.563

2.  Endocrine disruptor phthalates in bottled water: daily exposure and health risk assessment in pregnant and lactating women.

Authors:  Maryam Zare Jeddi; Noushin Rastkari; Reza Ahmadkhaniha; Masud Yunesian
Journal:  Environ Monit Assess       Date:  2016-08-24       Impact factor: 2.513

3.  Transdermal Uptake of Diethyl Phthalate and Di(n-butyl) Phthalate Directly from Air: Experimental Verification.

Authors:  Charles J Weschler; Gabriel Bekö; Holger M Koch; Tunga Salthammer; Tobias Schripp; Jørn Toftum; Geo Clausen
Journal:  Environ Health Perspect       Date:  2015-04-07       Impact factor: 9.031

4.  Removal of Diethylhexyl Phthalate from Hands by Handwashing: Evidence from Experimental N-of-1 and Crossover Designs.

Authors:  Pi-I D Lin; Chia-Fang Wu; Hwang-Shang Kou; Tzu-Ying Huang; Jentaie Shiea; Ming-Tsang Wu
Journal:  Sci Rep       Date:  2017-03-28       Impact factor: 4.379

5.  Exposure to phthalates and bisphenol A are associated with atopic dermatitis symptoms in children: a time-series analysis.

Authors:  Eun-Hye Kim; Byoung-Hak Jeon; Jihyun Kim; Young-Min Kim; Youngshin Han; Kangmo Ahn; Hae-Kwan Cheong
Journal:  Environ Health       Date:  2017-03-09       Impact factor: 5.984

6.  Analysis and Assessment of Exposure to Selected Phthalates Found in Children's Toys in Christchurch, New Zealand.

Authors:  Matthew James Ashworth; Andrew Chappell; Ellen Ashmore; Jefferson Fowles
Journal:  Int J Environ Res Public Health       Date:  2018-01-25       Impact factor: 3.390

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.