Literature DB >> 22125733

An uncommon presentation of giant cell tumor.

Hunaina Al-Kindi, Mina George, Gopal Malhotra, Khamis Al-Muzahmi.   

Abstract

Giant Cell Tumors commonly occur at the ends of long bones. However in rare cases, they can occur in the bones of the hands and feet. Tumors in these locations occur in younger patients; in addition, these tumors are more commonly multifocal and are associated with a higher risk for local recurrence than tumors at the ends of long bones. Since lesions in the small bones may be multifocal, a patient with a giant cell tumor of the small bones should undergo a skeletal survey to exclude similar lesions elsewhere. Primary surgical treatment ranges from curettage or excision with or without bone grafting to amputation. The success of surgical treatment depends on the completeness with which the tumor was removed. We are presenting a case report of a 34 year old female, who presented with a swelling in the right hand, following trauma. X-ray of the hand showed an osteolytic expansile lesion at the base of the 1(st) metacarpal bone. The lesion was initially curetted and then treated by local resection with bone grafting. Histological examination revealed a typical benign giant cell tumor composed of closely packed stromal cells with a variable admixture of giant cells. Follow up at the end of one year did not reveal any recurrence of the tumor.

Entities:  

Keywords:  1st metacarpal bone; Giant cell tumor

Year:  2011        PMID: 22125733      PMCID: PMC3215444          DOI: 10.5001/omj.2011.88

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  10 in total

1.  Giant cell tumor of the fourth metacarpal.

Authors:  K W McEnery; A K Raymond
Journal:  AJR Am J Roentgenol       Date:  1999-04       Impact factor: 3.959

2.  Giant cell tumours in hand bones.

Authors:  Muhammad Saeed Minhas; Ghulam Mehboob; Irfanullah Ansari
Journal:  J Coll Physicians Surg Pak       Date:  2010-07       Impact factor: 0.711

3.  Giant cell tumor of the hand: superior results with curettage, cryosurgery, and cementation.

Authors:  J C Wittig; B M Simpson; J Bickels; K L Kellar-Graney; M M Malawer
Journal:  J Hand Surg Am       Date:  2001-05       Impact factor: 2.230

4.  A giant-cell tumor in the hand presenting as an expansile diaphyseal lesion. Case report.

Authors:  J A Shaw; J F Mosher
Journal:  J Bone Joint Surg Am       Date:  1983-06       Impact factor: 5.284

5.  Giant cell tumor of the bones of the hand and foot.

Authors:  R Biscaglia; P Bacchini; F Bertoni
Journal:  Cancer       Date:  2000-05-01       Impact factor: 6.860

Review 6.  Multicentric giant cell tumour of bone.

Authors:  Mandeep S Dhillon; Prabhudev Prasad
Journal:  Acta Orthop Belg       Date:  2007-06       Impact factor: 0.500

7.  Chondroblastoma of the hands and feet.

Authors:  Jesse A Davila; Kimberly K Amrami; Murali Sundaram; Mark C Adkins; Krishnan K Unni
Journal:  Skeletal Radiol       Date:  2004-08-14       Impact factor: 2.199

8.  Caldwell Lecture. Giant cell tumor of bone: highlights of 407 cases.

Authors:  D C Dahlin
Journal:  AJR Am J Roentgenol       Date:  1985-05       Impact factor: 3.959

9.  Lesions of the bones of the hands and feet: a study of 50 cases.

Authors:  Shantveer G Uppin; C Sundaram; Matapathi Umamahesh; P Chandrashekar; Y Jyotsna Rani; V B N Prasad
Journal:  Arch Pathol Lab Med       Date:  2008-05       Impact factor: 5.534

10.  Giant cell tumor of the small bones of the hands and feet.

Authors:  L E Wold; R G Swee
Journal:  Semin Diagn Pathol       Date:  1984-08       Impact factor: 3.464

  10 in total
  1 in total

1.  Traumatic giant cell tumor of rib: A case report.

Authors:  Ying-Shian Chen; Hon-We Kao; Hsin-Ya Huang; Tsai-Wang Huang
Journal:  World J Clin Cases       Date:  2022-08-26       Impact factor: 1.534

  1 in total

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