OBJECTIVES: Consanguinity has been a long standing social habit among some Iranians. This study is aimed at determining the role of consanguinity on congenital malformations and the correlation of inbreeding coefficient with anomalies. METHODS: In this cross-sectional study, all the newborns who were born during 9 months period from April to December 2008. (n=1195) at Shahid Sadoughi hospital, Yazd, Iran were studied. RESULTS: From 1195 neonates, 300 (25%) were from consanguineous marriages and 895 (75%) were from non-familial marriages. From 45 cases with anomalies, 34 (2.8%) cases were from familial marriages, while only 11 (0.9%) cases were from non-familial marriages. There was a significant correlation between parental marriages and the prevalence of anomaly (p=0.018). CONCLUSION: The prevalence of congenital anomalies was mostly observed in consanguineous marriages compared to non consanguineous marriages.
OBJECTIVES: Consanguinity has been a long standing social habit among some Iranians. This study is aimed at determining the role of consanguinity on congenital malformations and the correlation of inbreeding coefficient with anomalies. METHODS: In this cross-sectional study, all the newborns who were born during 9 months period from April to December 2008. (n=1195) at Shahid Sadoughi hospital, Yazd, Iran were studied. RESULTS: From 1195 neonates, 300 (25%) were from consanguineous marriages and 895 (75%) were from non-familial marriages. From 45 cases with anomalies, 34 (2.8%) cases were from familial marriages, while only 11 (0.9%) cases were from non-familial marriages. There was a significant correlation between parental marriages and the prevalence of anomaly (p=0.018). CONCLUSION: The prevalence of congenital anomalies was mostly observed in consanguineous marriages compared to non consanguineous marriages.
Authors: K Rebekah Prasoona; B Srinadh; T Sunitha; M Sujatha; M L N Deepika; B Vijaya Lakshmi; Aruna Ramaiah; A Jyothy Journal: J Obstet Gynaecol India Date: 2014-10-29
Authors: Soudabeh Vatankhah; Mina Jalilvand; Samaneh Sarkhosh; Mina Azarmi; Mohammad Mohseni Journal: Iran J Public Health Date: 2017-06 Impact factor: 1.429