Literature DB >> 22125692

Correlation between Serum Level of Antiepileptic Drugs and their Side Effects.

Abbashar Hussein, Amira Abdulgalil, Faroug Omer, Hassan Eltoum, Ahmed Hamad, Omer El-Adil, Bedraldin Mubarak, Mohmad Malkaldar, Iway Idris, Yasin Alwidaa, Esam Mahmoud.   

Abstract

OBJECTIVES: The aim of the study is to investigate the relation between serum levels of anticonvulsants and their side effects.
METHODS: This is a prospective cross sectional hospital based study conducted at Al Shaab Teaching Hospital. 120 patients were included in the study. The AEDs used were phenytoin, phenobarbitone, carbamazibine, and sodium valproate.
RESULTS: The results showed that the side effects among the studied group were not uncommon.
CONCLUSION: There was no relationship between serum levels of AEDs and their side effects.

Entities:  

Year:  2010        PMID: 22125692      PMCID: PMC3215386          DOI: 10.5001/omj.2010.5

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  14 in total

1.  Compliance with health regimens of adolescents with epilepsy.

Authors:  H Kyngäs
Journal:  Seizure       Date:  2000-12       Impact factor: 3.184

2.  Automated homogeneous liposome immunoassay systems for anticonvulsant drugs.

Authors:  K Kubotsu; S Goto; M Fujita; H Tuchiya; M Kida; S Takano; S Matsuura; I Sakurabayashi
Journal:  Clin Chem       Date:  1992-06       Impact factor: 8.327

3.  Familial temporal lobe epilepsy: a common disorder identified in twins.

Authors:  S F Berkovic; A McIntosh; R A Howell; A Mitchell; L J Sheffield; J L Hopper
Journal:  Ann Neurol       Date:  1996-08       Impact factor: 10.422

4.  Measuring anti-convulsant levels in the accident and emergency department.

Authors:  R McGlone; P Pritty
Journal:  Arch Emerg Med       Date:  1986-06

5.  Expanding the international classification of seizures to provide localization information.

Authors:  H O Lüders; R Burgess; S Noachtar
Journal:  Neurology       Date:  1993-09       Impact factor: 9.910

6.  Appropriateness of antiepileptic drug level monitoring.

Authors:  R A Schoenenberger; M J Tanasijevic; A Jha; D W Bates
Journal:  JAMA       Date:  1995 Nov 22-29       Impact factor: 56.272

Review 7.  Some common issues in the use of antiepileptic drugs.

Authors:  Jorge J Asconapé
Journal:  Semin Neurol       Date:  2002-03       Impact factor: 3.420

8.  Cross-sensitivity of skin rashes with antiepileptic drug use.

Authors:  L J Hirsch; H Arif; E A Nahm; R Buchsbaum; S R Resor; C W Bazil
Journal:  Neurology       Date:  2008-11-04       Impact factor: 9.910

Review 9.  Focal neuronal migration disorders and intractable partial epilepsy: a study of 30 patients.

Authors:  A Palmini; F Andermann; A Olivier; D Tampieri; Y Robitaille; E Andermann; G Wright
Journal:  Ann Neurol       Date:  1991-12       Impact factor: 10.422

Review 10.  The clinical impact of pharmacogenetics on the treatment of epilepsy.

Authors:  Wolfgang Löscher; Ulrich Klotz; Fritz Zimprich; Dieter Schmidt
Journal:  Epilepsia       Date:  2008-07-08       Impact factor: 5.864

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  1 in total

1.  Phenytoin intoxication with no symptoms correlated with serum drug level: a case study.

Authors:  Mucahit Avcil; Ali Duman; Kenan Ahmet Turkdogan; Mucahit Kapci; Ayhan Akoz; Selcuk Eren Canakci; Yunus Emre Ozluer
Journal:  Pan Afr Med J       Date:  2015-11-24
  1 in total

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