Genbin Shi1, Xinhua Ji. 1. Biomolecular Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute, 1050 Boyles Street, Frederick, MD 21702, USA.
Abstract
Reported are the synthesis of two intermediates for derivatization at position 6 of 7,7-dimethyl-7,8-dihydropterin: 6-carboxylic acid ethyl ester-7,7-dimethyl-7,8-dihydropterin, which is a novel compound, and 6-aldehyde-7,7-dimethyl-7,8-dihydropterin, which is synthesized by a new method with a yield of 90%.
Reported are the synthesis of two intermediates for derivatization at position 6 of 7,7-dimethyl-7,8-dihydropterin: n class="Chemical">6-carboxylic acid ethyl ester-7,7-dimethyl-7,8-dihydropterin, which is a novel compound, and 6-aldehyde-7,7-dimethyl-7,8-dihydropterin, which is synthesized by a new method with a yield of 90%.
Authors: M Hennig; G E Dale; A D'arcy; F Danel; S Fischer; C P Gray; S Jolidon; F Müller; M G Page; P Pattison; C Oefner Journal: J Mol Biol Date: 1999-03-26 Impact factor: 5.469
Authors: Colin J Suckling; Colin L Gibson; Judith K Huggan; Raghavendar R Morthala; Brendan Clarke; Suma Kununthur; Roger M Wadsworth; Simon Daff; Davide Papale Journal: Bioorg Med Chem Lett Date: 2008-01-30 Impact factor: 2.823