Literature DB >> 22124544

Amyopathic dermatomyositis developing rapidly progressive interstitial lung disease with elevation of anti-CADM-140/MDA5 autoantibodies.

Shinji Sato1, Masataka Kuwana, Takashi Fujita, Yasuo Suzuki.   

Abstract

Anti-clinically amyopathic dermatomyositis (CADM)-140/MDA5 autoantibodies are specifically detected in patients with dermatomyositis and are known to have a strong association with rapidly progressive interstitial lung disease (RP-ILD). Here we report an amyopathic dermatomyositis (ADM) patient who developed RP-ILD characterized by elevated anti-CADM-140/MDA5 titer. Respiratory symptoms gradually improved, and anti-CADM-140/MDA5 titer decreased in parallel to below the cutoff level. It may be useful to quantify CADM-140-specific autoantibodies for monitoring disease activity in patients with ADM and RP-ILD.

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Year:  2011        PMID： 22124544     DOI： 10.1007/s10165-011-0558-9

Source DB:  PubMed          Journal:  Mod Rheumatol        ISSN： 1439-7595            Impact factor:   3.023


  10 in total

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Review 2.  Hypomyopathic dermatomyositis associated with interstitial lung disease and good response to mycophenolate mofetil: case-based review.

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Journal:  Clin Rheumatol       Date:  2017-05-09       Impact factor: 2.980

3.  Incidence and impact of interstitial lung disease and malignancy in patients with polymyositis, dermatomyositis, and clinically amyopathic dermatomyositis: a retrospective cohort study.

Authors:  Satoshi Ikeda; Machiko Arita; Kenta Misaki; Shohei Mishima; Takuya Takaiwa; Akihiro Nishiyama; Akihiro Ito; Kenjiro Furuta; Toshihide Yokoyama; Fumiaki Tokioka; Maki Noyama; Hiroshige Yoshioka; Tadashi Ishida
Journal:  Springerplus       Date:  2015-05-28

Review 4.  The significance of autoantibodies to DFS70/LEDGFp75 in health and disease: integrating basic science with clinical understanding.

Authors:  Robert L Ochs; Michael Mahler; Anamika Basu; Leslimar Rios-Colon; Tino W Sanchez; Luis E Andrade; Marvin J Fritzler; Carlos A Casiano
Journal:  Clin Exp Med       Date:  2015-06-19       Impact factor: 3.984

5.  The Serum Ferritin Level Is Associated with the Treatment Responsivity for Rapidly Progressive Interstitial Lung Disease with Amyopathic Dermatomyositis, Irrespective of the Anti-MDA5 Antibody Level.

Authors:  Takeshi Osawa; Kozo Morimoto; Yuka Sasaki; Shuichi Matsuda; Kazunari Yamana; Ryozo Yano; Takashi Uchiyama; Hajime Goto
Journal:  Intern Med       Date:  2017-11-01       Impact factor: 1.271

6.  Case Report: Treatment of Anti-MDA5-Positive Amyopathic Dermatomyositis Accompanied by a Rapidly Progressive Interstitial Lung Diseases With Methylprednisolone Pulse Therapy Combined With Cyclosporine A and Hydroxychloroquine.

Authors:  Qia-Chun Zhang; Min-Ying Liu; Zhi-Xin Chen; Yimin Talia Chen; Chang-Song Lin; Qiang Xu
Journal:  Front Med (Lausanne)       Date:  2020-11-27

7.  Noninvasive positive pressure ventilator deteriorates the outcome of pneumomediastinum in anti-MDA5 antibody-positive clinically amyopathic dermatomyositis.

Authors:  Mengmeng Zhou; Yan Ye; Ninghui Yan; Xinyue Lian; Chunde Bao; Qiang Guo
Journal:  Clin Rheumatol       Date:  2020-01-15       Impact factor: 2.980

8.  A Case of Polymyxin b-Immobilized Fiber Column Treatment for Rapidly Progressive Interstitial Pneumonia Associated with Clinically Amyopathic Dermatomyositis.

Authors:  Oh Sasaki; Makoto Dohi; Hiroaki Harada; Mitsuru Imamura; Yumi Tsuchida; Kensuke Yamaguchi; Toshihiko Komai; Kazuhiko Yamamoto
Journal:  Case Rep Med       Date:  2013-07-28

9.  Anti-MDA5 antibodies in a large Mediterranean population of adults with dermatomyositis.

Authors:  Moises Labrador-Horrillo; Maria Angeles Martinez; Albert Selva-O'Callaghan; Ernesto Trallero-Araguas; Eva Balada; Miquel Vilardell-Tarres; Cándido Juárez
Journal:  J Immunol Res       Date:  2014-02-04       Impact factor: 4.818

10.  Clinical Utility of an Enzyme-Linked Immunosorbent Assay for Detecting Anti-Melanoma Differentiation-Associated Gene 5 Autoantibodies.

Authors:  Shinji Sato; Akihiro Murakami; Akiko Kuwajima; Kazuhiko Takehara; Tsuneyo Mimori; Atsushi Kawakami; Michiaki Mishima; Takafumi Suda; Mariko Seishima; Manabu Fujimoto; Masataka Kuwana
Journal:  PLoS One       Date:  2016-04-26       Impact factor: 3.240
  10 in total

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