Literature DB >> 221239

On the effects of thiamphenicol and chloramphenicol on nucleic acid and protein synthesis in rabbit bone marrow cells in vivo and in vitro.

W Nijhof, P K Wierenga.   

Abstract

Besides the in vivo effects of thiamphenicol (TAP), this study shows the in vitro effects of TAP and D- and L-threo-chloramphenicol (CAP) on the synthesis of DNA, RNA, protein and hemoglobin in marrow cells and reticulocytes. The experiments make it likely that TAP exerts its action on a stem cell in a proliferating phase.

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Year:  1979        PMID： 221239     DOI： 10.1007/bf01960400

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  EFFECT OF CHLORAMPHENICOL ON PROTEIN SYNTHESIS.

Authors:  A S WEISBERGER; S WOLFE
Journal:  Fed Proc       Date:  1964 Sep-Oct

2.  The effect of chloramphenicol on the incorporation of labeled amino acids into proteins by isolated subcellular fractions from rat liver.

Authors:  R RENDI
Journal:  Exp Cell Res       Date:  1959-08       Impact factor: 3.905

3.  The effect of thiamphenicol on the production of immature red blood cells under anaemic conditions.

Authors:  W Nijhof; P K Wierenga; S Kardaun
Journal:  Br J Haematol       Date:  1977-05       Impact factor: 6.998

4.  The interference of chloramphenicol and thiamphenicol with the biogenesis of mitochondria in animal tissues. A possible clue to the toxic action.

Authors:  W Nijhof; A M Kroon
Journal:  Postgrad Med J       Date:  1974-10       Impact factor: 2.401

5.  The effect of chloramphenicol on mitochondrial protein synthesis in Neurospora crassa.

Authors:  H Weiss; A Schwab; G von Jagow
Journal:  Postgrad Med J       Date:  1974-10       Impact factor: 2.401

6.  Comparative metabolic effects of chloramphenicol and thiamphenicol in mammalian cells.

Authors:  A A Yunis; D R Manyan; G K Arimura
Journal:  Postgrad Med J       Date:  1974-10       Impact factor: 2.401

7.  Chloramphenicol and protein synthesis in mammalian cells.

Authors:  L Zelkowitz; G K Arimura; A A Yunis
Journal:  J Lab Clin Med       Date:  1968-04

8.  Antibiotics: a tool in the search for the degree of autonomy of mitochondria in higher animals.

Authors:  A M Kroon; H de Vries
Journal:  Symp Soc Exp Biol       Date:  1970

9.  Chloramphenicol induced inhibition of platelet protein synthesis: in vitro and in vivo studies.

Authors:  G Agam; S Gasner; H Bessler; P Fishman; M Djaldetti
Journal:  Br J Haematol       Date:  1976-05       Impact factor: 6.998

10.  Embryonic development and mitochondrial function. 2. Thiamphenicol induced embryotoxicity.

Authors:  R Bass; D Oerter
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-02       Impact factor: 3.000
  10 in total
  1 in total

1.  Thiamphenicol induced bone marrow suppression as a therapy of myeloproliferative diseases.

Authors:  P Fröhli; C Graf; K Rhyner
Journal:  Blut       Date:  1984-12
  1 in total

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