Literature DB >> 22122526

Colonoscopy-associated perforation: a 7-year survey of in-hospital frequency, treatment and outcome in a German university hospital.

A F Hagel1, F Boxberger, W Dauth, H P Kessler, M F Neurath, M Raithel.   

Abstract

AIM: Perforation occurs rarely after colonoscopy, but is associated with high morbidity and mortality. In this study, we assessed the perforation rate in our hospital, its clinical diagnosis and the long-term outcome.
METHOD: During the study period, 7535 examinations were performed, of which 4830 were diagnostic and 2705 therapeutic. The latter included polypectomy, endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), dilatation and argon plasma coagulation (APC).
RESULTS: Overall, 25 (0.33%) perforations occurred with two (0.026%) procedure-related deaths. Seven (0.14%) perforations occurred during a diagnostic procedure and 18 (0.67%) occurred during a therapeutic procedure. Dilation, submusous resection (SMR) and APC accounted for more perforations than polypectomy or diagnostic colonoscopy. Pre-existing gastrointestinal disease was present in 24 (96%) perforations. Three (12%) patients were treated conservatively and 22 (88%) underwent surgery. The site of perforation was closed by suture in four (18%) patients and resected with colonic anastomosis in five (23%) patients. Two patients underwent endoscopic clipping. A stoma was created after resection in 13 (59%) patients.
CONCLUSION: Death from perforation after colonoscopy is rare, occurring in 1/3500 examinations. The risk is increased in therapeutic colonoscopy and in the presence of previous gastrointestinal disease. Dilatation, SMR and APC appeared to confer a higher risk of perforation than polypectomy or diagnostic colonoscopy.
© 2011 The Authors. Colorectal Disease © 2011 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Mesh:

Year:  2012        PMID: 22122526     DOI: 10.1111/j.1463-1318.2011.02899.x

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  12 in total

1.  Prompt management is most important for colonic perforation after colonoscopy.

Authors:  Hyun-Ho Kim; Bong-Hyeon Kye; Hyung-Jin Kim; Hyeon-Min Cho
Journal:  Ann Coloproctol       Date:  2014-10-28

2.  Outcome, comorbidity, hospitalization and 30-day mortality after closure of acute perforations and postoperative anastomotic leaks by the over-the-scope clip (OTSC) in an unselected cohort of patients.

Authors:  M Raithel; H Albrecht; W Scheppach; M Farnbacher; W Haupt; A F Hagel; V Schellerer; F Vitali; M F Neurath; H T Schneider
Journal:  Surg Endosc       Date:  2016-09-15       Impact factor: 4.584

3.  Endoscopic full-thickness resection (EFTR) in the lower gastrointestinal tract.

Authors:  H Albrecht; M Raithel; A Braun; A Nagel; A Stegmaier; K Utpatel; C Schäfer
Journal:  Tech Coloproctol       Date:  2019-07-31       Impact factor: 3.781

Review 4.  Use of Evidence-Based Herbal Medicines for Patients with Functional Gastrointestinal Disorders: A Conceptional Framework for Risk-Benefit Assessment and Regulatory Approaches.

Authors:  Gerald Holtmann; Dietmar Schrenk; Ahmed Madisch; Hans D Allescher; Gudrun Ulrich-Merzenich; Fermin Mearin; Dominique Larrey; Peter Malfertheiner
Journal:  Dig Dis       Date:  2019-11-26       Impact factor: 2.404

5.  Colonoscopic perforations: Single center experience and review of the literature.

Authors:  Şükrü Çolak; Bünyamin Gürbulak; Hasan Bektaş; Ekrem Çakar; Yiğit Düzköylü; Savaş Bayrak; Ayhan Güneyi
Journal:  Turk J Surg       Date:  2017-04-25

6.  Prevalence and clinical features of coagulation syndrome after endoscopic submucosal dissection for colorectal neoplasms.

Authors:  Mi Jin Hong; Jeong Hwan Kim; Sun-Young Lee; In-Kyung Sung; Hyung Seok Park; Chan Sup Shim
Journal:  Dig Dis Sci       Date:  2014-12-13       Impact factor: 3.199

7.  Analysis of colonoscopic perforations at a local clinic and a tertiary hospital.

Authors:  Toshihiko Sagawa; Satoru Kakizaki; Haruhisa Iizuka; Yasuhiro Onozato; Naondo Sohara; Shinichi Okamura; Masatomo Mori
Journal:  World J Gastroenterol       Date:  2012-09-21       Impact factor: 5.742

8.  The Clinical Utility of Over-the-Scope Clip for the Treatment of Gastrointestinal Defects.

Authors:  Ido Mizrahi; Rana Eltawil; Nadav Haim; Sami A Chadi; Bo Shen; Tolga Erim; Giovanna DaSilva; Steven D Wexner
Journal:  J Gastrointest Surg       Date:  2016-09-29       Impact factor: 3.452

9.  Cost-Effectiveness Analysis of Five Competing Strategies for the Management of Multiple Recurrent Community-Onset Clostridium difficile Infection in France.

Authors:  Emilie Baro; Tatiana Galperine; Fanette Denies; Damien Lannoy; Xavier Lenne; Pascal Odou; Benoit Guery; Benoit Dervaux
Journal:  PLoS One       Date:  2017-01-19       Impact factor: 3.240

10.  Unexpected Delayed Colon Perforation after the Endoscopic Submucosal Dissection with Snaring of a Laterally Spreading Tumor.

Authors:  Young Bo Ko; Jeong-Mi Lee; Wan Soo Kim; Min Seob Kwak; Ji Wan Lee; Dong Yeol Shin; Dong-Hoon Yang; Jeong-Sik Byeon
Journal:  Clin Endosc       Date:  2015-11-30
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