Literature DB >> 22122128

Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer's disease.

Tao Ma1, Eric Klann1.   

Abstract

Mounting evidence suggests that amyloid beta-induced impairments in synaptic plasticity that is accompanied by cognitive decline and dementia represent key pathogenic steps of Alzheimer's disease. In this study, we review recent advances in the study of the molecular and cellular mechanisms underlying Alzheimer's disease-associated synaptic dysfunction and memory deficits, and how these mechanisms could provide novel avenues for therapeutic intervention to treat this devastating neurodegenerative disease.
© 2011 The Authors. Journal of Neurochemistry © 2011 International Society for Neurochemistry.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 22122128      PMCID： PMC3254830          DOI： 10.1111/j.1471-4159.2011.07506.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


  50 in total

Review 1.  Therapeutic Potential of Glucagon-Like Peptide-1 Cleavage Product for Alzheimer's Disease.

Authors:  Stephen M Day; Tao Ma
Journal:  Neurosci Bull       Date:  2019-03-07       Impact factor: 5.203

Review 2.  Therapeutic Potential of AMP-Activated Protein Kinase in Alzheimer's Disease.

Authors:  Xin Wang; Helena R Zimmermann; Tao Ma
Journal:  J Alzheimers Dis       Date:  2019       Impact factor: 4.472

Review 3.  Oxidative Stress and the Central Nervous System.

Authors:  Samina Salim
Journal:  J Pharmacol Exp Ther       Date:  2016-10-17       Impact factor: 4.030

4.  Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.

Authors:  Tao Ma; Yiran Chen; Valerie Vingtdeux; Haitian Zhao; Benoit Viollet; Philippe Marambaud; Eric Klann
Journal:  J Neurosci       Date:  2014-09-03       Impact factor: 6.167

5.  Repression of the eIF2α kinase PERK alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.

Authors:  Wenzhong Yang; Xueyan Zhou; Helena R Zimmermann; Douglas R Cavener; Eric Klann; Tao Ma
Journal:  Neurobiol Aging       Date:  2016-02-13       Impact factor: 4.673

Review 6.  Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders.

Authors:  Lucio G Costa; Toby B Cole; Khoi Dao; Yu-Chi Chang; Jacki Coburn; Jacqueline M Garrick
Journal:  Pharmacol Ther       Date:  2020-03-09       Impact factor: 12.310

7.  Glucagon-like peptide-1 cleavage product GLP-1(9-36) amide rescues synaptic plasticity and memory deficits in Alzheimer's disease model mice.

Authors:  Tao Ma; Xueliang Du; Joseph E Pick; Guangzhi Sui; Michael Brownlee; Eric Klann
Journal:  J Neurosci       Date:  2012-10-03       Impact factor: 6.167

Review 8.  Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer's Disease.

Authors:  Lan Guo; Jing Tian; Heng Du
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

9.  Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease.

Authors:  Brenna C Beckelman; Stephen Day; Xueyan Zhou; Maggie Donohue; Gunnar K Gouras; Eric Klann; C Dirk Keene; Tao Ma
Journal:  J Alzheimers Dis       Date:  2016-09-06       Impact factor: 4.472

Review 10.  Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer's disease Neurons.

Authors:  Ravi Rajmohan; P Hemachandra Reddy
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.