| Literature DB >> 22121915 |
Hun Young Kim1, Jian-Yuan Li, Sungkyung Kim, Kyungsoo Oh.
Abstract
Stereodivergent catalytic asymmetric conjugate reactions of glycine (ket)imines with nitroalkenes have been achieved using various chiral catalyst systems derived from a multidentate amino alcohol (1). The stepwise nature of the [3 + 2] cycloaddition reactions of N-metalated azomethine ylides has also been demonstrated by highly enantio- and diastereoselective syntheses of exo-5 and endo-8 from the respective syn-4 and anti-7 conjugate addition products in a one-pot tandem fashion.Entities:
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Year: 2011 PMID： 22121915 DOI： 10.1021/ja2100356
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419