Literature DB >> 22119152

Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines.

Carla S Francisco1, Lígia R Rodrigues, Nuno M F S A Cerqueira, Ana M F Oliveira-Campos, Lígia M Rodrigues.   

Abstract

The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumor cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder transitional cell carcinoma) were evaluated, and discussed in terms of structure-activity relationship.
Copyright © 2011 Elsevier Masson SAS. All rights reserved.

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Year:  2011        PMID: 22119152     DOI: 10.1016/j.ejmech.2011.11.005

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  3 in total

Review 1.  Effects of psoralens as anti-tumoral agents in breast cancer cells.

Authors:  Maria Luisa Panno; Francesca Giordano
Journal:  World J Clin Oncol       Date:  2014-08-10

2.  Hesperidin exhibits in vitro and in vivo antitumor effects in human osteosarcoma MG-63 cells and xenograft mice models via inhibition of cell migration and invasion, cell cycle arrest and induction of mitochondrial-mediated apoptosis.

Authors:  Guang-Yu Du; Sheng-Wei He; Lu Zhang; Chuan-Xiu Sun; Li-Dong Mi; Zue-Gang Sun
Journal:  Oncol Lett       Date:  2018-09-14       Impact factor: 2.967

3.  Evaluation of the antioxidant capacity of synthesized coumarins.

Authors:  Damiana R Vianna; Guilherme Bubols; Gabriela Meirelles; Bárbara V Silva; Alessandra Da Rocha; Maurício Lanznaster; José Maria Monserrat; Solange Cristina Garcia; Gilsane Von Poser; Vera Lucia Eifler-Lima
Journal:  Int J Mol Sci       Date:  2012-06-13       Impact factor: 6.208

  3 in total

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