| Literature DB >> 22118745 |
Abstract
Multiple myeloma (MM) is a malignancy of terminally differentiated plasma cells characterized by complex genetic aberrations and heterogeneous outcomes. Over the past 25 years, cytogenetic analysis has played a key role in the diagnosis and management of MM. This article reviews the conventional cytogenetics, molecular cytogenetics, and genomic diagnostics of MM and highlights a few recent clinical trials that demonstrate the impact of genetic risk stratification on the treatment of this plasma cell malignancy.Entities:
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Year: 2011 PMID： 22118745 DOI： 10.1016/j.cll.2011.08.009
Source DB: PubMed Journal: Clin Lab Med ISSN： 0272-2712 Impact factor: 1.935