Literature DB >> 22118519

A new angle on TCR activation.

Jia-huai Wang1, Ellis L Reinherz.   

Abstract

Functional cognate T cell recognition is mediated via the interaction of a T cell receptor complex with its pMHC ligand. Adams et al. (2011) in this issue of Immunity provide evidence that docking geometry may impact 2D binding and T cell activation.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID: 22118519      PMCID: PMC3371662          DOI: 10.1016/j.immuni.2011.11.008

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  10 in total

1.  Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.

Authors:  Y H Ding; B M Baker; D N Garboczi; W E Biddison; D C Wiley
Journal:  Immunity       Date:  1999-07       Impact factor: 31.745

2.  The alphabeta T cell receptor is an anisotropic mechanosensor.

Authors:  Sun Taek Kim; Koh Takeuchi; Zhen-Yu J Sun; Maki Touma; Carlos E Castro; Amr Fahmy; Matthew J Lang; Gerhard Wagner; Ellis L Reinherz
Journal:  J Biol Chem       Date:  2009-09-15       Impact factor: 5.157

3.  An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.

Authors:  K C Garcia; M Degano; R L Stanfield; A Brunmark; M R Jackson; P A Peterson; L Teyton; I A Wilson
Journal:  Science       Date:  1996-10-11       Impact factor: 47.728

4.  Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.

Authors:  J H Wang; R Meijers; Y Xiong; J H Liu; T Sakihama; R Zhang; A Joachimiak; E L Reinherz
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-04       Impact factor: 11.205

5.  Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody.

Authors:  J Wang; K Lim; A Smolyar; M Teng; J Liu; A G Tse; J Liu; R E Hussey; Y Chishti; C T Thomson; R M Sweet; S G Nathenson; H C Chang; J C Sacchettini; E L Reinherz
Journal:  EMBO J       Date:  1998-01-02       Impact factor: 11.598

6.  T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.

Authors:  Jarrett J Adams; Samanthi Narayanan; Baoyu Liu; Michael E Birnbaum; Andrew C Kruse; Natalie A Bowerman; Wei Chen; Aron M Levin; Janet M Connolly; Cheng Zhu; David M Kranz; K Christopher Garcia
Journal:  Immunity       Date:  2011-11-23       Impact factor: 31.745

7.  CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor.

Authors:  Natalie A Borg; Kwok S Wun; Lars Kjer-Nielsen; Matthew C J Wilce; Daniel G Pellicci; Ruide Koh; Gurdyal S Besra; Mandvi Bharadwaj; Dale I Godfrey; James McCluskey; Jamie Rossjohn
Journal:  Nature       Date:  2007-06-20       Impact factor: 49.962

8.  Force generation upon T cell receptor engagement.

Authors:  Julien Husson; Karine Chemin; Armelle Bohineust; Claire Hivroz; Nelly Henry
Journal:  PLoS One       Date:  2011-05-10       Impact factor: 3.240

9.  Cutting Edge: mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling.

Authors:  Ya-Chen Li; Bing-Mae Chen; Pei-Chun Wu; Tian-Lu Cheng; Lung-Sen Kao; Mi-Hua Tao; Andre Lieber; Steve R Roffler
Journal:  J Immunol       Date:  2010-04-30       Impact factor: 5.426

10.  Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.

Authors:  Jürgen Kuball; Beate Hauptrock; Victoria Malina; Edite Antunes; Ralf-Holger Voss; Matthias Wolfl; Roland Strong; Matthias Theobald; Philip D Greenberg
Journal:  J Exp Med       Date:  2009-01-26       Impact factor: 14.307

  10 in total
  2 in total

Review 1.  The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function.

Authors:  Jia-huai Wang; Ellis L Reinherz
Journal:  Immunol Rev       Date:  2012-11       Impact factor: 12.988

Review 2.  An old Twist in HLA-A: CDR3α Hook up at an R65-joint.

Authors:  Joseph S Murray
Journal:  Front Immunol       Date:  2015-05-27       Impact factor: 7.561

  2 in total

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