Literature DB >> 22116526

A rare manifestation of cricopharyngeal myopathy presenting with dysphagia in sarcoidosis.

Kaori Nishikubo1, Masamitsu Hyodo, Miyuki Kawakami, Taisuke Kobayashi.   

Abstract

Sarcoidosis is a systemic inflammatory granulomatous disease that affects multiple organs in the body; however, dysphagia is a relatively rare manifestation at early stages. Dysphagia in sarcoidosis is attributed to many mechanisms, such as mediastinal lymphadenopathy, esophageal or laryngeal involvement, cranial neuropathy, and brainstem infiltration. In this article, we report an extremely rare case with sarcoidosis who presented with dysphagia due to isolated cricopharyngeal myopathy. The 75-year-old woman presented with slowly progressive swallowing difficulty and videofluorography showed insufficient opening of the upper esophageal sphincter. On presentation, she had no cranial nerve or central nervous system impairments. A cricopharyngeal myotomy was performed, and histopathological study revealed a significant inflammatory change with non-necrotizing granulomas within the muscle tissue. We concluded that this was a very rare case of sarcoidosis presenting with localized cricopharyngeal myopathy. Postoperatively, a contracture of the esophageal entrance was successfully released and the dysphagia was alleviated.

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Year:  2011        PMID: 22116526     DOI: 10.1007/s00296-011-2242-y

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   2.631


  21 in total

1.  Granulomatous myositis: a clinical study of thirteen cases.

Authors:  Karine Le Roux; Nathalie Streichenberger; Christophe Vial; Philippe Petiot; Leonard Feasson; Françoise Bouhour; Jacques Ninet; Florence Lachenal; Christiane Broussolle; Pascal Sève
Journal:  Muscle Nerve       Date:  2007-02       Impact factor: 3.217

Review 2.  Reversible esophageal motility disorder in a patient with sarcoidosis.

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3.  Acute reversible dysphagia and dysphonia as initial manifestations of sarcoidosis.

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Journal:  Hepatogastroenterology       Date:  1999 Jul-Aug

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Authors:  M S Cappell
Journal:  Am J Gastroenterol       Date:  1995-03       Impact factor: 10.864

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Journal:  Radiology       Date:  1990-07       Impact factor: 11.105

6.  Sarcoid peripheral neuropathy.

Authors:  G Zuniga; A H Ropper; J Frank
Journal:  Neurology       Date:  1991-10       Impact factor: 9.910

7.  Neurosarcoidosis presenting as Guillain-Barré-like syndrome. A case report and review of the literature.

Authors:  Firas Fahoum; Vivian E Drory; Josephine Issakov; Miri Y Neufeld
Journal:  J Clin Neuromuscul Dis       Date:  2009-09

Review 8.  Myopathy in sarcoidosis: clinical and pathologic study of four cases and review of the literature.

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Journal:  Semin Arthritis Rheum       Date:  1987-05       Impact factor: 5.532

9.  Intense muscle uptake of gallium-67 in a patient with sarcoidosis.

Authors:  I H Liem; M Drent; E Antevska; R J Lamers; G A Heidendal
Journal:  J Nucl Med       Date:  1998-09       Impact factor: 10.057

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Authors:  J S Bower; J E Belen; J G Weg; D R Dantzker
Journal:  Am Rev Respir Dis       Date:  1980-08
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  3 in total

1.  Esophageal sarcoidosis: a review of cases and an update.

Authors:  Albin Abraham; Rabab Hajar; Ravi Virdi; Jaspreet Singh; Paul Mustacchia
Journal:  ISRN Gastroenterol       Date:  2013-03-05

2.  Dysphagia, an uncommon initial presentation of sarcoidosis.

Authors:  Navjot Somal; Ravi Karan; Aarti Maharaj; Jeff Halperin; Brent Boodhai; Jeffrey Lipton; Daniel J Masri; Kamlesh Kumar
Journal:  Respir Med Case Rep       Date:  2022-04-04

Review 3.  Autoimmune Neurogenic Dysphagia.

Authors:  Panos Stathopoulos; Marinos C Dalakas
Journal:  Dysphagia       Date:  2021-07-05       Impact factor: 2.733

  3 in total

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