| Literature DB >> 22115718 |
Jianbin Chao1, Hongfang Wang, Wei Zhao, Min Zhang, Liwei Zhang.
Abstract
The inclusion complexation behavior of chlorogenic acid (CGA) with the hydroxypropyl-β-cyclodextrin (HP-β-CD) was investigated in both solution and the solid state by UV-vis and fluorescence spectroscopy, infrared spectroscopy (IR), NMR spectroscopy as well as differential scanning calorimetry (DSC). The experimental results indicate that CGA is able to form an inclusion complex with HP-β-CD. The inclusion complex has a stoichiometry of 1:1 and the formation constant was calculated to be 155.7 M(-1). The antioxidant activity of CGA on complexation with HP-β-CD increased as compared to uncomplexed CGA. NMR spectroscopic studies show that the aromatic ring and the vinyl group of CGA are deeply included inside the CD cavity.Entities:
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Year: 2011 PMID： 22115718 DOI： 10.1016/j.ijbiomac.2011.11.008
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953