Literature DB >> 22115417

DNA methylation as a biomarker for neuropsychiatric diseases.

Sanxi Ai1, Lu Shen, Jifeng Guo, Xiang Feng, Beisha Tang.   

Abstract

ABSTRACT DNA methylation, which has been investigated extensively recently, has been studied in various human diseases, including cancer, and the analysis of DNA methylation has provided useful biomarkers for diagnosing cancer, monitoring treatment, and predicting the prognosis of cancer. Recently, aberrant DNA methylation has been reported in various neuropsychiatric diseases in both postmortem brains and peripheral blood cells. This review summarizes the current evidence on aberrant DNA methylation in peripheral blood cells from patients with neurodevelopmental, neurodegenerative, and psychiatric disorders, and we propose that DNA methylation could be a novel biomarker for these disorders.

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Year:  2012        PMID： 22115417     DOI： 10.3109/00207454.2011.637654

Source DB:  PubMed          Journal:  Int J Neurosci        ISSN： 0020-7454            Impact factor:   2.292


  11 in total

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4.  Epigenetic DNA Methylation Profiling with MSRE: A Quantitative NGS Approach Using a Parkinson's Disease Test Case.

Authors:  Adam G Marsh; Matthew T Cottrell; Morton F Goldman
Journal:  Front Genet       Date:  2016-11-02       Impact factor: 4.599

Review 5.  "Gestaltomics": Systems Biology Schemes for the Study of Neuropsychiatric Diseases.

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Review 6.  Molecular Factors Involved in Spinal Muscular Atrophy Pathways as Possible Disease-modifying Candidates.

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8.  Multilocus loss of DNA methylation in individuals with mutations in the histone H3 lysine 4 demethylase KDM5C.

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Journal:  BMC Med Genomics       Date:  2013-01-28       Impact factor: 3.063

9.  Epigenetic Variability across Human Populations: A Focus on DNA Methylation Profiles of the KRTCAP3, MAD1L1 and BRSK2 Genes.

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Review 10.  Omics Application in Animal Science-A Special Emphasis on Stress Response and Damaging Behaviour in Pigs.

Authors:  Claudia Kasper; David Ribeiro; André M de Almeida; Catherine Larzul; Laurence Liaubet; Eduard Murani
Journal:  Genes (Basel)       Date:  2020-08-11       Impact factor: 4.096
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