Literature DB >> 22115034

Cytotoxic triterpene saponins from Clematis mandshurica.

Yu-Xin He1, Ling Li, Kang Zhang, Zhong-Rong Liu.   

Abstract

Two new triterpene saponins, mandshunosides A and B (1 and 2), were isolated from the roots and rhizomes of Clematis mandshurica. Their structures were elucidated on the basis of spectroscopic evidence and hydrolysis products. Compounds 1 and 2 showed inhibitory activities against two colorectal human cancer cells HCT 116 (IC₅₀ 2.1 μM for 1 and 2.5 μM for 2) and HT-29 (IC₅₀ 3.7 μM for 1 and 3.3 μM for 2).

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Year:  2011        PMID: 22115034     DOI: 10.1080/10286020.2011.618453

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  3 in total

1.  Cytotoxic Activities of Total Saponins from Plena Clematis on Human Tumor Cell Lines In Vitro.

Authors:  Fu-Rong Zhu; Yong-Ning Li; Shu-Lan He; Qian-Shun Chen; Xun-Yu Xu
Journal:  Chin J Integr Med       Date:  2018-06-21       Impact factor: 1.978

Review 2.  Anticancer Chemodiversity of Ranunculaceae Medicinal Plants: Molecular Mechanisms and Functions.

Authors:  Da-Cheng Hao; Chun-Nian He; Jie Shen; Pei-Gen Xiao
Journal:  Curr Genomics       Date:  2017-02       Impact factor: 2.236

3.  Characterization of new microsatellite markers based on the transcriptome sequencing of Clematis finetiana.

Authors:  Zhigao Liu; Weili Shao; Yamei Shen; Mengcheng Ji; Wenchao Chen; Ying Ye; Yongbao Shen
Journal:  Hereditas       Date:  2018-05-15       Impact factor: 3.271

  3 in total

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