Literature DB >> 22114760

Design of multivalent galactosyl carborane as a targeting specific agent for potential application to boron neutron capture therapy.

Chian-Hui Lai1, Yu-Chuan Lin, Fong-In Chou, Chien-Fu Liang, En-Wei Lin, Yung-Jen Chuang, Chun-Cheng Lin.   

Abstract

A multivalent galactosyl carborane derivative 10 (dendritic glyco-borane, DGB) was synthesized and demonstrated as a potential cell-targeting agent in BNCT with HepG2 cells. DGB 10 improved the delivery of boron to HepG2 cells and neutron irradiation data show DGB 10 with ten-fold improvement at killing the HepG2 cells over BSH. This journal is © The Royal Society of Chemistry 2012

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Year:  2011        PMID： 22114760     DOI： 10.1039/c1cc14447b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Evaluation of a Novel Boron-Containing α-D-Mannopyranoside for BNCT.

Authors:  Takao Tsurubuchi; Makoto Shirakawa; Wataru Kurosawa; Kayo Matsumoto; Risa Ubagai; Hiroshi Umishio; Yasuyo Suga; Junko Yamazaki; Akihiro Arakawa; Yutaka Maruyama; Takuya Seki; Yusuke Shibui; Fumiyo Yoshida; Alexander Zaboronok; Minoru Suzuki; Yoshinori Sakurai; Hiroki Tanaka; Kei Nakai; Eiichi Ishikawa; Akira Matsumura
Journal:  Cells       Date:  2020-05-21       Impact factor: 6.600

Review 2.  Boron delivery agents for neutron capture therapy of cancer.

Authors:  Rolf F Barth; Peng Mi; Weilian Yang
Journal:  Cancer Commun (Lond)       Date:  2018-06-19

3.  Boron-Containing Probes for Non-optical High-Resolution Imaging of Biological Samples.

Authors:  Selda Kabatas; Paola Agüi-Gonzalez; Kim-Ann Saal; Sebastian Jähne; Felipe Opazo; Silvio O Rizzoli; Nhu T N Phan
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-06       Impact factor: 15.336

4.  Enlargement of a Modular System-Synthesis and Characterization of an s-Triazine-Based Carboxylic Acid Ester Bearing a Galactopyranosyl Moiety and an Enormous Boron Load.

Authors:  Martin Kellert; Peter Lönnecke; Bernd Riedl; Johannes Koebberling; Evamarie Hey-Hawkins
Journal:  Molecules       Date:  2019-09-10       Impact factor: 4.411
  4 in total

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