OBJECTIVE: The aim of this study was to analyze the factors that were associated with the development of osteomyelitis during the treatment of mandibular fractures. MATERIAL AND METHODS: The data of 3188 patients with mandibular fractures treated during 2002-2009 were analyzed. Traumatic osteomyelitis of the mandible was diagnosed in 207 patients. The background factors of complications were studied and compared with the control group (100 patients) not having complications after treatment of mandibular fractures. The data of clinical, roentgenologic, microbiological, and immunological investigations were analyzed. A logistic regression model was developed to identify the factors for osteomyelitis development. RESULTS: The treatment in 6.5% of patients was complicated with osteomyelitis; 88.5% of these patients were men, and more than 80% of patients were younger than 50 years. In 86.8% of cases, Staphylococcus species were isolated, with Staphylococcus aureus accounting for 69.1% of cases. The following factors were found to be associated with osteomyelitis development: immunity dysfunction, caries-affected teeth at the fracture line, mobile fractured bones, bone fixation after more than 7 days following trauma, healthy teeth at the fracture line, insufficient bone reposition, and bone fixation after 3-7 days following trauma. CONCLUSION: Comparative analysis of factors influencing the treatment results revealed a great importance of immunological and dental status and microflora at the affected site. Insufficient or late reposition and fixation of fractured bone fragments play a significant role in the healing process.
OBJECTIVE: The aim of this study was to analyze the factors that were associated with the development of osteomyelitis during the treatment of mandibular fractures. MATERIAL AND METHODS: The data of 3188 patients with mandibular fractures treated during 2002-2009 were analyzed. Traumatic osteomyelitis of the mandible was diagnosed in 207 patients. The background factors of complications were studied and compared with the control group (100 patients) not having complications after treatment of mandibular fractures. The data of clinical, roentgenologic, microbiological, and immunological investigations were analyzed. A logistic regression model was developed to identify the factors for osteomyelitis development. RESULTS: The treatment in 6.5% of patients was complicated with osteomyelitis; 88.5% of these patients were men, and more than 80% of patients were younger than 50 years. In 86.8% of cases, Staphylococcus species were isolated, with Staphylococcus aureus accounting for 69.1% of cases. The following factors were found to be associated with osteomyelitis development: immunity dysfunction, caries-affected teeth at the fracture line, mobile fractured bones, bone fixation after more than 7 days following trauma, healthy teeth at the fracture line, insufficient bone reposition, and bone fixation after 3-7 days following trauma. CONCLUSION: Comparative analysis of factors influencing the treatment results revealed a great importance of immunological and dental status and microflora at the affected site. Insufficient or late reposition and fixation of fractured bone fragments play a significant role in the healing process.
Authors: Emma Watson; Brandon T Smith; Mollie M Smoak; Alexander M Tatara; Sarita R Shah; Hannah A Pearce; Katie J Hogan; Jonathan Shum; James C Melville; Issa A Hanna; Nagi Demian; Joseph C Wenke; George N Bennett; Jeroen J J P van den Beucken; John A Jansen; Mark E Wong; Antonios G Mikos Journal: Biomaterials Date: 2020-06-23 Impact factor: 12.479
Authors: Kevin Bertrand; Brigitte Lamy; Marie De Boutray; Jacques Yachouh; Sophie Galmiche; Pierre Leprêtre; Nicolas Menjot de Champfleur; Jacques Reynes; Vincent Le Moing; David Morquin Journal: Eur J Clin Microbiol Infect Dis Date: 2018-03-07 Impact factor: 3.267