Literature DB >> 2211046

Serial proton magnetic resonance spectroscopy of ischemic brain injury in humans.

M J Fenstermacher1, P A Narayana.   

Abstract

Four patients were observed serially with 1H magnetic resonance spectroscopy (MRS) at times ranging from 3 days to 10 weeks after a documented ischemic event. Spectra were obtained from 8 cc volumes in infarcted regions and contralateral matched normal regions. Reproducible variations in n-acetyl aspartate (NAA), creatine + phosphocreatine (Cr + PCr), and the sequential changes in lactate and lipid resonances are related to the pathophysiology of stroke. A conspicuous lack of significant change in the choline (Cho) resonance with concomitant decrease in NAA and Cr + PCr is reported as a possible marker of ischemic injury.

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Year:  1990        PMID： 2211046     DOI： 10.1097/00004424-199009000-00016

Source DB:  PubMed          Journal:  Invest Radiol        ISSN： 0020-9996            Impact factor:   6.016


  11 in total

1.  Prognostic significance of metabolic changes detected by proton magnetic resonance spectroscopy in ischaemic stroke.

Authors:  F Federico; I L Simone; C Conte; V Lucivero; P Giannini; M Liguori; E Picciola; C Tortorella
Journal:  J Neurol       Date:  1996-03       Impact factor: 4.849

Review 2.  N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology.

Authors:  John R Moffett; Brian Ross; Peethambaran Arun; Chikkathur N Madhavarao; Aryan M A Namboodiri
Journal:  Prog Neurobiol       Date:  2007-01-05       Impact factor: 11.685

3.  1H spectroscopic imaging of acute head injury--evidence of diffuse axonal injury.

Authors:  J M Wild; C S Macmillan; J M Wardlaw; I Marshall; J Cannon; V J Easton; P J Andrews
Journal:  MAGMA       Date:  1999-05       Impact factor: 2.310

4.  Exchange rates of creatine kinase metabolites: feasibility of imaging creatine by chemical exchange saturation transfer MRI.

Authors:  Mohammad Haris; Ravi Prakash Reddy Nanga; Anup Singh; Kejia Cai; Feliks Kogan; Hari Hariharan; Ravinder Reddy
Journal:  NMR Biomed       Date:  2012-03-20       Impact factor: 4.044

5.  Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy.

Authors:  Z Wang; A R Bogdan; R A Zimmerman; D A Gusnard; J S Leigh; K Ohene-Frempong
Journal:  Neuroradiology       Date:  1992       Impact factor: 2.804

6.  Creatine CEST MRI for Differentiating Gliomas with Different Degrees of Aggressiveness.

Authors:  Kejia Cai; Rong-Wen Tain; Xiaohong Joe Zhou; Frederick C Damen; Alessandro M Scotti; Hari Hariharan; Harish Poptani; Ravinder Reddy
Journal:  Mol Imaging Biol       Date:  2017-04       Impact factor: 3.488

7.  Spatial integration of multimodal brain images in cerebral infarction.

Authors:  N M Knufman; P A van den Elsen; J P Cillessen; J W van Isselt; C A Tulleken
Journal:  Brain Topogr       Date:  1992       Impact factor: 3.020

8.  Serial Cerebral Metabolic Changes in Patients With Ischemic Stroke Treated With Autologous Bone Marrow Derived Mononuclear Cells.

Authors:  Muhammad E Haque; Refaat E Gabr; Sarah D George; Seth B Boren; Farhaan S Vahidy; Xu Zhang; Octavio D Arevalo; Susan Alderman; Ponnada A Narayana; Khader M Hasan; Elliott R Friedman; Clark W Sitton; Sean I Savitz
Journal:  Front Neurol       Date:  2019-02-25       Impact factor: 4.003

9.  N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.

Authors:  Katharina Huber; Dina C Hofer; Sophie Trefely; Helmut J Pelzmann; Corina Madreiter-Sokolowski; Madalina Duta-Mare; Stefanie Schlager; Gert Trausinger; Sarah Stryeck; Wolfgang F Graier; Dagmar Kolb; Christoph Magnes; Nathaniel W Snyder; Andreas Prokesch; Dagmar Kratky; Tobias Madl; Kathryn E Wellen; Juliane G Bogner-Strauss
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2018-08-31       Impact factor: 5.011

10.  Serial Metabolic Evaluation of Perihematomal Tissues in the Intracerebral Hemorrhage Pig Model.

Authors:  Muhammad E Haque; Refaat E Gabr; Sarah D George; Xiurong Zhao; Seth B Boren; Xu Zhang; Shun-Ming Ting; Gunghua Sun; Khader M Hasan; Sean Savitz; Jaroslaw Aronowski
Journal:  Front Neurosci       Date:  2019-08-21       Impact factor: 4.677
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