Literature DB >> 22109004

High-sensitivity in vivo THz transmission imaging of early human breast cancer in a subcutaneous xenograft mouse model.

Hua Chen1, Te-Hsuen Chen, Tzu-Fang Tseng, Jen-Tang Lu, Chung-Chiu Kuo, Shih-Chen Fu, Wen-Jeng Lee, Yuan-Fu Tsai, Yi-You Huang, Eric Y Chuang, Yuh-Jing Hwang, Chi-Kuang Sun.   

Abstract

We performed in vivo THz transmission imaging study on a subcutaneous xenograft mouse model for early human breast cancer detection. With a THz-fiber-scanning transmission imaging system, we continuously monitored the growth of human breast cancer in mice. Our in vivo study not only indicates that THz transmission imaging can distinguish cancer from the surrounding fatty tissue, but also with a high sensitivity. Our in vivo study on the subcutaneous xenograft mouse model will encourage broad and further investigations for future early cancer screening by using THz imaging system.
© 2011 Optical Society of America

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Year:  2011        PMID: 22109004     DOI: 10.1364/OE.19.021552

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  8 in total

1.  The potential of terahertz imaging for cancer diagnosis: A review of investigations to date.

Authors:  Calvin Yu; Shuting Fan; Yiwen Sun; Emma Pickwell-Macpherson
Journal:  Quant Imaging Med Surg       Date:  2012-03

2.  Screening and analysis of breast cancer genes regulated by the human mammary microenvironment in a humanized mouse model.

Authors:  Mingjie Zheng; Jue Wang; Lijun Ling; Dandan Xue; Shui Wang; Yi Zhao
Journal:  Oncol Lett       Date:  2016-10-24       Impact factor: 2.967

3.  Pulsed terahertz imaging of breast cancer in freshly excised murine tumors.

Authors:  Tyler Bowman; Tanny Chavez; Kamrul Khan; Jingxian Wu; Avishek Chakraborty; Narasimhan Rajaram; Keith Bailey; Magda El-Shenawee
Journal:  J Biomed Opt       Date:  2018-02       Impact factor: 3.170

4.  Human mammary microenvironment better regulates the biology of human breast cancer in humanized mouse model.

Authors:  Ming-Jie Zheng; Jue Wang; Lu Xu; Xiao-Ming Zha; Yi Zhao; Li-Jun Ling; Shui Wang
Journal:  Med Oncol       Date:  2015-01-09       Impact factor: 3.064

5.  Molecular pathological recognition of freshly excised human glioma using terahertz ATR spectroscopy.

Authors:  Ning Mu; Chuanyan Yang; Degang Xu; Shi Wang; Kang Ma; Ying Lai; Peiwen Guo; Shuixian Zhang; Yuye Wang; Hua Feng; Tunan Chen; Jianquan Yao
Journal:  Biomed Opt Express       Date:  2021-12-07       Impact factor: 3.732

6.  Mammary tumors in Sprague Dawley rats induced by N-ethyl-N-nitrosourea for evaluating terahertz imaging of breast cancer.

Authors:  Nagma Vohra; Tanny Chavez; Joel R Troncoso; Narasimhan Rajaram; Jingxian Wu; Patricia N Coan; Todd A Jackson; Keith Bailey; Magda El-Shenawee
Journal:  J Med Imaging (Bellingham)       Date:  2021-04-26

7.  Clinical Diagnosis of Gastric Cancer by High-Sensitivity THz Fiber-Based Fast-Scanning Near-Field Imaging.

Authors:  Hua Chen; Juan Han; Shihua Ma; Xiao Li; Tianzhu Qiu; Xiaofeng Chen
Journal:  Cancers (Basel)       Date:  2022-08-15       Impact factor: 6.575

8.  Use of finite difference time domain simulations and Debye theory for modelling the terahertz reflection response of normal and tumour breast tissue.

Authors:  Anthony J Fitzgerald; Emma Pickwell-MacPherson; Vincent P Wallace
Journal:  PLoS One       Date:  2014-07-10       Impact factor: 3.240

  8 in total

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