Literature DB >> 22108700

Pretreatment thrombocytosis: a prognostic marker for oral squamous cell carcinoma?

Steffen Kargus1, Franz E Weber, Heinz T Luebbers, Wolfgang Zemann, Klaus W Graetz, Astrid L Kruse.   

Abstract

PURPOSE: Thrombocytosis associated with poorer prognoses seems to be a frequent preoperative finding in different kind of cancers. The aim of the present study was to evaluate whether thrombocytosis can be used as a prognostic marker for oral squamous cell carcinoma (SCC).
METHODS: Altogether, 288 patients with oral SCC were considered, as well as all platelet counts between 1 and 5 days prior to surgical treatment, recurrence rate, and lymph node metastasis. The minimum follow-up time was 12 months.
RESULTS: The mean preoperative thrombocyte score of the patients who received surgery was 259.55 ± 83.8 Tsd/μl; 273 out of 288 patients were in the normal thrombocyte range, and 12 had a thrombocytosis. From 51 patients with recurrence, three were in the thrombocytosis group, and 45 patients with recurrence were in the normal thrombocyte range.
CONCLUSION: The present results do not confirm that thrombocytosis can be seen as marker for poor tumor prognosis.

Entities:  

Mesh:

Year:  2011        PMID: 22108700     DOI: 10.1007/s10006-011-0305-6

Source DB:  PubMed          Journal:  Oral Maxillofac Surg        ISSN: 1865-1550


  22 in total

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2.  Prognostic importance of DNA from human papillomavirus in patients with oral squamous cell carcinoma.

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